Reactive oxygen species bridge the gap between chronic inflammation and tumor development

W Yu, Y Tu, Z Long, J Liu, D Kong… - Oxidative medicine …, 2022 - Wiley Online Library
According to numerous animal studies, adverse environmental stimuli, including physical,
chemical, and biological factors, can cause low‐grade chronic inflammation and subsequent …

Established and Emerging Cancer Therapies and Cardiovascular System: Focus on Hypertension—Mechanisms and Mitigation

LE Butel-Simoes, TJ Haw, T Williams, S Sritharan… - …, 2023 - Am Heart Assoc
Cardiovascular disease and cancer are 2 of the leading causes of death worldwide.
Although improvements in outcomes have been noted for both disease entities, the success …

[HTML][HTML] Identification of immune-related key genes in the peripheral blood of ischaemic stroke patients using a weighted gene coexpression network analysis and …

PF Zheng, LZ Chen, P Liu, HW Pan, WJ Fan… - Journal of Translational …, 2022 - Springer
Background The immune system plays a vital role in the pathological process of ischaemic
stroke. However, the exact immune-related mechanism remains unclear. The current …

The Relationship between Association between Blood Pressure and Risk of Cancer Development

N Tzenios, M Tazanios, M Chahine - 2022 - preprints.org
Abstract Background of the Study: We investigated the link between hypertension and
cancer since it has been suggested that hypertension may raise the long-term risk of cancer …

[HTML][HTML] The relationship between metabolic dysfunction-associated fatty liver disease and the incidence rate of extrahepatic cancer

S Wei, Y Hao, X Dong, J Huang, K Huang… - Frontiers in …, 2023 - frontiersin.org
Background The associations between metabolic dysfunction-associated fatty liver disease
(MAFLD) and cancer development, especially extrahepatic cancers, are unknown. The aims …

Mechanistic science in cardiovascular-oncology: the way forward to maximise anti-cancer drug effects and minimise cardiovascular toxicity

NN Lang, RM Touyz - Clinical Science, 2021 - portlandpress.com
Dramatic improvements in cancer survival have arisen because of the rapid development of
novel anti-cancer therapies. The potential for cardiovascular toxicity associated with these …

[HTML][HTML] Several first-line anti-hypertensives act on fibrosarcoma progression and PD1ab blockade therapy

J Sun, C Zhang, X Su, H Zhou, S Zhou, M Jiang… - Journal of Orthopaedic …, 2024 - Springer
Purpose Patients are typically diagnosed with both hypertension and fibrosarcoma. Medical
oncologists must prescribe suitable anti-hypertensive medications while considering anti …

[HTML][HTML] Complications and comorbidities associated with antineoplastic chemotherapy: Rethinking drug design and delivery for anticancer therapy

X Mao, S Wu, D Huang, C Li - Acta Pharmaceutica Sinica B, 2024 - Elsevier
Despite the considerable advancements in chemotherapy as a cornerstone modality in
cancer treatment, the prevalence of complications and pre-existing diseases is on the rise …

Association between walking pace and risks of major chronic diseases in individuals with hypertension based on a prospective study in UK Biobank: Involvement of …

Y Peng, F Liu, P Wang, X Wang, C Si, J Gong… - Preventive …, 2024 - Elsevier
Objective Walking pace is associated with risks of major chronic diseases including cancer,
cardiovascular disease (CVD) and diabetes mellitus type 2 (T2DM) in the general …

High-fat diet-induced hyperinsulinemia promotes the development of prostate adenocarcinoma in prostate-specific Pten−/− mice

H Wang, W Yan, Y Sun, CS Yang - Carcinogenesis, 2022 - academic.oup.com
Metabolic syndrome (MetS) and its four clinical entities, central obesity, insulin resistance,
hypertension and dyslipidemia, are implicated in increasing the risk and mortality of cancer …