Polymeric materials have been used in a range of pharmaceutical and biotechnology
products for more than 40 years. These materials have evolved from their earlier use as …

Nanoparticles have received enormous attention as a promising tool to enhance target-
specific drug delivery and diagnosis. Various in vitro and in vivo techniques are used to …

Micelles formed through the self-assembly of block copolymers have been widely used to
encapsulate highly hydrophobic drugs to increase their effective solubility. However, this …

This tutorial review presents an overview of strategies for the synthesis and fabrication of
organic nanomaterials, specifically those with potential for use in medical applications …

Polymeric micelles are supramolecular, core-shell nanoparticles that offer considerable
advantages for cancer diagnosis and therapy. Their relatively small size (10–100 nm), ability …

Cancer drug delivery achieving high therapeutic efficacy and low side effects requires a
nanocarrier to tightly retain the drug, efficiently reach the tumor, then quickly enter the tumor …

Thermosensitive amphiphilic block copolymers self-assemble into micelles above their
lower critical solution temperature in water, however, the micelles generally display …

Combinatorial chemo and gene therapy provides a promising way to cure drug-resistant
cancer, since the codelivered functional nucleic acids can regulate drug resistance genes …

Block copolymers spontaneously assemble into nanoscaled polymeric micelles, which have
significant potential as drug carriers. Following much work in related fields over the last …

One-third of drugs in development are water insoluble and one-half fail in trials because of
poor pharmacokinetics. Block copolymer micelles are nanosized particles that can solubilize …