A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro) degenerative processes in that …
This paper reviews the body of evidence that major depression is accompanied by a
decreased antioxidant status and by induction of oxidative and nitrosative (IO&NS) …
decreased antioxidant status and by induction of oxidative and nitrosative (IO&NS) …
Primary prevention of ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council: cosponsored by the …
Background and Purpose—This guideline provides an overview of the evidence on various
established and potential stroke risk factors and provides recommendations for the reduction …
established and potential stroke risk factors and provides recommendations for the reduction …
Aspirin resistance
GJ Hankey, JW Eikelboom - The Lancet, 2006 - thelancet.com
Aspirin resistance is the inability of aspirin to reduce platelet production of thromboxane A 2
and thereby platelet activation and aggregation. Increasing degrees of aspirin resistance …
and thereby platelet activation and aggregation. Increasing degrees of aspirin resistance …
Non-steroidal anti-inflammatory drugs for cancer prevention: promise, perils and pharmacogenetics
CM Ulrich, J Bigler, JD Potter - Nature Reviews Cancer, 2006 - nature.com
Aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) show indisputable
promise as chemopreventive agents. Possible targets include cancers of the colon, stomach …
promise as chemopreventive agents. Possible targets include cancers of the colon, stomach …
What does minor elevation of C-reactive protein signify?
I Kushner, D Rzewnicki, D Samols - The American journal of medicine, 2006 - Elsevier
Reports of the predictive value of minor elevation of serum C-reactive protein (CRP) levels
(between 3 and 10 mg/L) for atherosclerotic events have generated considerable interest, as …
(between 3 and 10 mg/L) for atherosclerotic events have generated considerable interest, as …
The link between prostanoids and cardiovascular diseases
L Beccacece, P Abondio, C Bini, S Pelotti… - International Journal of …, 2023 - mdpi.com
Cardiovascular diseases are the leading cause of global deaths, and many risk factors
contribute to their pathogenesis. In this context, prostanoids, which derive from arachidonic …
contribute to their pathogenesis. In this context, prostanoids, which derive from arachidonic …
Identification of functional genetic variants in cyclooxygenase-2 and their association with risk of esophageal cancer
Background & Aims: Overexpression of cyclooxygenase-2 (COX-2) is implicated in many
steps of cancer development. Single nucleotide polymorphisms (SNPs) in the COX-2 …
steps of cancer development. Single nucleotide polymorphisms (SNPs) in the COX-2 …
Nonvalidation of reported genetic risk factors for acute coronary syndrome in a large-scale replication study
ContextGiven the numerous, yet inconsistent, reports of genetic variants being associated
with acute coronary syndromes (ACS), there is a need for comprehensive validation of ACS …
with acute coronary syndromes (ACS), there is a need for comprehensive validation of ACS …
Oxidative enzymopathies and vascular disease
JA Leopold, J Loscalzo - Arteriosclerosis, thrombosis, and vascular …, 2005 - Am Heart Assoc
In the vasculature, reactive oxygen species (ROS) generated by both mitochondrial
respiration and enzymatic sources serve as integral components of cellular signaling and …
respiration and enzymatic sources serve as integral components of cellular signaling and …
Cyclooxygenase-2 expression and inhibition in atherothrombosis
Arachidonic acid metabolism plays an important role in acute ischemic syndromes affecting
the coronary or cerebrovascular territory, as reflected by biochemical measurements of …
the coronary or cerebrovascular territory, as reflected by biochemical measurements of …