Revisiting the mechanisms of immune evasion employed by human parasites

M Chulanetra, W Chaicumpa - Frontiers in cellular and infection …, 2021 - frontiersin.org
For the establishment of a successful infection, ie, long-term parasitism and a complete life
cycle, parasites use various diverse mechanisms and factors, which they may be inherently …

Evasion of innate immunity by parasitic protozoa

D Sacks, A Sher - Nature immunology, 2002 - nature.com
Parasitic protozoa are a major cause of global infectious disease. These eukaryotic
pathogens have evolved with the vertebrate immune system and typically produce long …

Does the Leishmania major paradigm of pathogenesis and protection hold for New World cutaneous leishmaniases or the visceral disease?

D McMahon‐Pratt, J Alexander - Immunological reviews, 2004 - Wiley Online Library
Parasitic protozoa of the genus Leishmania have provided a useful perspective for
immunologists in terms of host defense mechanisms critical for the resolution of infection …

Cysteine peptidases as virulence factors of Leishmania

JC Mottram, GH Coombs, J Alexander - Current opinion in microbiology, 2004 - Elsevier
Leishmania mexicana amastigotes are particularly rich in cysteine peptidases (CPs), which
play important roles in facilitating the survival and growth of the parasites in mammals. The …

Malaria and leishmaniasis: Updates on co-infection

U Ornellas-Garcia, P Cuervo… - Frontiers in …, 2023 - frontiersin.org
Malaria and leishmaniasis are endemic parasitic diseases in tropical and subtropical
countries. Although the overlap of these diseases in the same host is frequently described …

Proteinases as virulence factors in Leishmania spp. infection in mammals

M Silva-Almeida, BAS Pereira… - Parasites & vectors, 2012 - Springer
Leishmania parasites cause human tegumentary and visceral infections that are commonly
referred to as leishmaniasis. Despite the high incidence and prevalence of cases …

The amastigote forms of Leishmania are experts at exploiting host cell processes to establish infection and persist

PE Kima - International journal for parasitology, 2007 - Elsevier
Leishmania are dimorphic protozoan parasites that live as flagellated forms in the gut of their
sandfly vector and as aflagellated forms in their mammalian hosts. Although both parasite …

Rapid Sequestration of Leishmania mexicana by Neutrophils Contributes to the Development of Chronic Lesion

BP Hurrell, S Schuster, E Grün, M Coutaz… - PLoS …, 2015 - journals.plos.org
The protozoan Leishmania mexicana parasite causes chronic non-healing cutaneous
lesions in humans and mice with poor parasite control. The mechanisms preventing the …

Leishmania Hijacks Myeloid Cells for Immune Escape

M Martínez-López, M Soto, S Iborra… - Frontiers in …, 2018 - frontiersin.org
Protozoan parasites of the Leishmania genus are the causative agents of leishmaniasis, a
group of neglected tropical diseases whose clinical manifestations vary depending on the …

Cutting edge: Th2 response induction by dendritic cells: a role for CD40

AS MacDonald, AD Straw, NM Dalton… - The Journal of …, 2002 - journals.aai.org
We investigated the influence of dendritic cell (DC) CD40 expression on Th2 and Th1
development by in vivo transfer of Ag-pulsed bone marrow-derived DC generated from wild …