Shiga Toxin–Producing Escherichia coli and the Hemolytic–Uremic Syndrome

SB Freedman, NCAJ van de Kar… - New England Journal of …, 2023 - Mass Medical Soc
Shiga Toxin–Producing Escherichia coli and the Hemolytic–Uremic Syndrome | New England
Journal of Medicine Skip to main content The New England Journal of Medicine homepage …

Enterohemorrhagic Escherichia coli and a Fresh View on Shiga Toxin-Binding Glycosphingolipids of Primary Human Kidney and Colon Epithelial Cells and Their …

J Detzner, G Pohlentz, J Müthing - International Journal of Molecular …, 2022 - mdpi.com
Enterohemorrhagic Escherichia coli (EHEC) are the human pathogenic subset of Shiga
toxin (Stx)-producing E. coli (STEC). EHEC are responsible for severe colon infections …

Bloody Diarrhea and Shiga Toxin–Producing Escherichia Coli Hemolytic Uremic Syndrome in Children: Data from the ItalKid-HUS Network

G Ardissino, C Vignati, C Masia, V Capone… - The Journal of …, 2021 - Elsevier
Objective To analyze the results of an enhanced laboratory-surveillance protocol for bloody
diarrhea aimed at identifying children with Shiga toxin–producing Escherichia coli (STEC) …

A novel Shiga toxin 2a neutralizing antibody therapeutic with low immunogenicity and high efficacy

ME Kirkland, S Patfield, AC Hughes… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
Shiga toxin-producing Escherichia coli infections are difficult to treat due to the risk of
antibiotic-induced stress upregulating the production of toxins, medical treatment is …

Genomic analysis of Shiga toxin-producing Escherichia coli O157:H7 from cattle and pork-production related environments

P Zhang, S Essendoubi, J Keenliside, T Reuter… - npj Science of …, 2021 - nature.com
Abstract Three E. coli O157: H7 outbreaks have been attributed to contaminated pork in
Alberta, Canada, recently. This study investigates the phylogenetic relatedness of E. coli …

Severely ill pediatric patients with Shiga toxin-associated hemolytic uremic syndrome (STEC-HUS) who suffered from multiple organ involvement in the early stage

M Luna, M Kamariski, I Principi, V Bocanegra… - Pediatric …, 2021 - Springer
Abstract Background Shiga toxin-producing Escherichia coli-associated hemolytic uremic
syndrome (STEC-HUS) is the main cause of pediatric acute kidney injury (AKI) in Argentina …

[HTML][HTML] The diverse landscape of AB5-type toxins

PI Brown, A Ojiakor, AJ Chemello, CC Fowler - Engineering Microbiology, 2023 - Elsevier
ABSTRACT AB 5-type toxins are a group of secreted protein toxins that are central virulence
factors for bacterial pathogens such as Shigella dysenteriae, Vibrio cholerae, Bordetella …

Hemolytic uremic syndrome associated with Shiga toxin-producing Escherichia coli infection in Argentina: update of serotypes and genotypes and their relationship …

LF Alconcher, A Balestracci, PA Coccia, AC Suarez… - Pediatric …, 2021 - Springer
Abstract Background Shiga toxin-producing Escherichia coli (STEC) infection is the most
common cause of hemolytic uremic syndrome (HUS). Only few studies correlated serotypes …

Gastrointestinal involvement in STEC-associated hemolytic uremic syndrome: 10 years in a pediatric center

M Giordano, O Iacoviello, L Santangelo, M Martino… - Pediatric …, 2024 - Springer
Background The gastrointestinal (GI) tract represents one of the main targets of typical
hemolytic uremic syndrome (HUS) in children. In this observational study, we tried to …

The Virulence of Escherichia coli O157:H7 Isolates in Mice Depends on Shiga Toxin Type 2a (Stx2a)-Induction and High Levels of Stx2a in Stool

JR Hauser, RR Atitkar, CD Petro, RL Lindsey… - Frontiers in Cellular …, 2020 - frontiersin.org
In this study we compared nine Shiga toxin (Stx)-producing Escherichia coli O157: H7
patient isolates for Stx levels, stx-phage insertion site (s), and pathogenicity in a …