Progress in the development of ultrasound-mediated gene delivery systems utilizing nano-and microbubbles

R Suzuki, Y Oda, N Utoguchi, K Maruyama - Journal of controlled release, 2011 - Elsevier
Recently, ultrasound-mediated gene delivery with nano-and microbubbles was developed
as a novel non-viral vector system. In this gene delivery system, microstreams and microjets …

The role of Ca2+ in ultrasound-elicited bioeffects: progress, perspectives and prospects

MA Hassan, P Campbell, T Kondo - Drug Discovery Today, 2010 - Elsevier
Intracellular calcium (Ca2+) transients have been observed in association with exposure to
therapeutic ultrasound and correlated to both early-and late-onset bioeffects. For example, it …

Sonoporation induces apoptosis and cell cycle arrest in human promyelocytic leukemia cells

W Zhong, WH Sit, JMF Wan, CH Alfred - Ultrasound in medicine & biology, 2011 - Elsevier
Despite being a transient biophysical phenomenon, sonoporation is known to disturb the
homeostasis of living cells. This work presents new evidence on how sonoporation may lead …

[HTML][HTML] Detection and comparison of reactive oxygen species (ROS) generated by chlorophyllin metal (Fe, Mg and Cu) complexes under ultrasonic and visible-light …

J Wang, Y Guo, J Gao, X Jin, Z Wang, B Wang… - Ultrasonics …, 2011 - Elsevier
In this paper, in order to examine the mechanisms of sonodynamic and photodynamic
reactions, the chlorophyllin metal (Chl-M (M= Fe, Mg and Cu)) complexes were irradiated by …

In vitro ultrasound experiments: Standing wave and multiple reflections influence on the outcome

W Secomski, K Bilmin, T Kujawska, A Nowicki, P Grieb… - Ultrasonics, 2017 - Elsevier
The purpose of this work was to determine the influence of standing waves and possible
multiple reflections under the conditions often encountered in examining the effects of …

Gene delivery systems by the combination of lipid bubbles and ultrasound

Y Negishi, Y Endo-Takahashi… - Drug discoveries & …, 2016 - jstage.jst.go.jp
Gene therapy is promising for the treatment of many diseases including cancers and genetic
diseases. From the viewpoint of safety, ultrasound (US)-mediated gene delivery with …

Effect of microbubbles on microfiltration pretreatment for seawater reverse osmosis membrane

MPO Gwenaelle, J Jung, Y Choi, S Lee - Desalination, 2017 - Elsevier
This study focused on the application of microbubbles (Mbs) to microfiltration (MF)
pretreatment for reverse osmosis (RO) desalination. Experiments were performed using …

[HTML][HTML] Low-frequency ultrasound-induced VEGF suppression and synergy with dendritic cell-mediated anti-tumor immunity in murine prostate cancer cells in vitro

W Zhang, WD Shou, YJ Xu, WK Bai, B Hu - Scientific reports, 2017 - nature.com
High tumor vascular endothelial growth factor (VEGF) levels are associated with poor
treatment outcomes in prostate cancer (PCa), and immune deficiency in the PCa …

[HTML][HTML] Study on characteristics of single cavitation bubble considering condensation and evaporation of kerosene steam under ultrasonic vibration honing

L Ye, X Zhu, L Wang, C Guo - Ultrasonics Sonochemistry, 2018 - Elsevier
Ultrasonic vibration honing technology is an effective means for materials difficult to
machine, where cavitation occurs in grinding fluid under the action of ultrasound. To …

Ultrasound-triggered PLGA microparticle destruction and degradation for controlled delivery of local cytotoxicity and drug release

KW Jang, D Seol, L Ding, DN Heo, SJ Lee… - International journal of …, 2018 - Elsevier
In this study, we investigated the low intensity ultrasound (US)-controlled delivery of local
cytotoxicity and drug release via induced destruction and degradation of microparticles …