[PDF][PDF] Hallmarks of aging: An expanding universe

C López-Otín, MA Blasco, L Partridge, M Serrano… - Cell, 2023 - cell.com
Aging is driven by hallmarks fulfilling the following three premises:(1) their age-associated
manifestation,(2) the acceleration of aging by experimentally accentuating them, and (3) the …

Fatigue in Alzheimer's disease: Biological basis and clinical management—a narrative review

D Angioni, J Raffin, PJ Ousset, J Delrieu… - Aging Clinical and …, 2023 - Springer
Background Fatigue is a common symptom in neurodegenerative diseases and is
associated with decreased cognitive performances. A full knowledge of the causes and …

[HTML][HTML] Senescence-related impairment of autophagy induces toxic intraneuronal amyloid-β accumulation in a mouse model of amyloid pathology

N Suelves, S Saleki, T Ibrahim, D Palomares… - Acta neuropathologica …, 2023 - Springer
Aging is the main risk factor for Alzheimer's disease (AD) and other neurodegenerative
pathologies, but the molecular and cellular changes underlying pathological aging of the …

[HTML][HTML] The role of cellular senescence in neurodegenerative diseases

Y Wang, K Kuca, L You, E Nepovimova, Z Heger… - Archives of …, 2024 - Springer
Increasing evidence has revealed that cellular senescence drives NDs, including
Alzheimer's disease (AD) and Parkinson's disease. Different senescent cell populations …

[HTML][HTML] Molecular determinants of neurocognitive deficits in glioma: based on 2021 WHO classification

K Zhang, T Yang, Y Xia, X Guo, W Chen… - Journal of Molecular …, 2024 - Springer
Cognitive impairment is a common feature among patients with diffuse glioma. The objective
of the study is to investigate the relationship between preoperative cognitive function and …

Telomere-induced senescence increases aberrant intraneuronal amyloid-β accumulation by impairing autophagy in a mouse model of Alzheimer's disease

N Suelves, S Saleki, T Ibrahim, D Palomares, C Vrancx… - bioRxiv, 2022 - biorxiv.org
Aging is a well-known risk factor for Alzheimer's disease (AD) and other neurodegenerative
pathologies, but the molecular and cellular changes occurring in the aging brain are poorly …