[HTML][HTML] The role of glutathione in protecting against the severe inflammatory response triggered by COVID-19

F Silvagno, A Vernone, GP Pescarmona - Antioxidants, 2020 - mdpi.com
The novel COVID-19 pandemic is affecting the world's population differently: mostly in the
presence of conditions such as aging, diabetes and hypertension the virus triggers a lethal …

[HTML][HTML] The multifaceted therapeutic role of N-acetylcysteine (NAC) in disorders characterized by oxidative stress

G Raghu, M Berk, PA Campochiaro… - Current …, 2021 - ncbi.nlm.nih.gov
Oxidative stress, which results in the damage of diverse biological molecules, is a ubiquitous
cellular process implicated in the etiology of many illnesses. The sulfhydryl-containing …

Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease 2017 report. GOLD executive summary

CF Vogelmeier, GJ Criner, FJ Martinez… - American journal of …, 2017 - atsjournals.org
This Executive Summary of the Global Strategy for the Diagnosis, Management, and
Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 …

N‐acetylcysteine: a review of clinical usefulness (an old drug with new tricks)

GK Schwalfenberg - Journal of nutrition and metabolism, 2021 - Wiley Online Library
Objective. To review the clinical usefulness of N‐acetylcysteine (NAC) as treatment or
adjunctive therapy in a number of medical conditions. Use in Tylenol overdose, cystic …

[HTML][HTML] N-Acetylcysteine (NAC): Impacts on Human Health

MCS Tenório, NG Graciliano, FA Moura, ACM Oliveira… - Antioxidants, 2021 - mdpi.com
N-acetylcysteine (NAC) is a medicine widely used to treat paracetamol overdose and as a
mucolytic compound. It has a well-established safety profile, and its toxicity is uncommon …

[HTML][HTML] Therapeutic host-directed strategies to improve outcome in tuberculosis

C Young, G Walzl, N Du Plessis - Mucosal immunology, 2020 - Elsevier
Abstract Bacille Calmette-Guérin (BCG) is the only licenced tuberculosis (TB) vaccine, but
has limited efficacy against pulmonary TB disease development and modest protection …

[HTML][HTML] New perspectives for mucolytic, anti-inflammatory and adjunctive therapy with 1, 8-cineole in COPD and asthma: review on the new therapeutic approach

LJ Juergens, H Worth, UR Juergens - Advances in therapy, 2020 - Springer
Abstract The mucolytic monoterpene 1, 8-cineole (eucalyptol), the major constituent of
eucalyptus species, is well known for its anti-inflammatory, antioxidant, bronchodilatory …

[HTML][HTML] Oxidative stress in COPD: sources, markers, and potential mechanisms

AJA McGuinness, E Sapey - Journal of clinical medicine, 2017 - mdpi.com
Markers of oxidative stress are increased in chronic obstructive pulmonary disease (COPD)
and reactive oxygen species (ROS) are able to alter biological molecules, signaling …

Prevention of COPD exacerbations: a European respiratory Society/American thoracic Society guideline

JA Wedzicha, PMA Calverley, RK Albert… - European …, 2017 - Eur Respiratory Soc
This document provides clinical recommendations for the prevention of chronic obstructive
pulmonary disease (COPD) exacerbations. It represents a collaborative effort between the …

A systematic review with meta-analysis of dual bronchodilation with LAMA/LABA for the treatment of stable COPD

L Calzetta, P Rogliani, MG Matera, M Cazzola - Chest, 2016 - Elsevier
Background The wide availability of long-acting muscarinic antagonist (LAMA)/long-acting
β2-agonist (LABA) fixed-dose combinations (FDCs) in the absence of head-to-head …