[HTML][HTML] Biological and environmental predictors of heterogeneity in neurocognitive ageing: Evidence from Betula and other longitudinal studies
Individual differences in cognitive performance increase with advancing age, reflecting
marked cognitive changes in some individuals along with little or no change in others …
marked cognitive changes in some individuals along with little or no change in others …
Discovery of shared genomic loci using the conditional false discovery rate approach
In recent years, genome-wide association study (GWAS) sample sizes have become larger,
the statistical power has improved and thousands of trait-associated variants have been …
the statistical power has improved and thousands of trait-associated variants have been …
White matter disturbances in major depressive disorder: a coordinated analysis across 20 international cohorts in the ENIGMA MDD working group
Alterations in white matter (WM) microstructure have been implicated in the pathophysiology
of major depressive disorder (MDD). However, previous findings have been inconsistent …
of major depressive disorder (MDD). However, previous findings have been inconsistent …
Genome-wide association analysis of 19,629 individuals identifies variants influencing regional brain volumes and refines their genetic co-architecture with cognitive …
Volumetric variations of the human brain are heritable and are associated with many brain-
related complex traits. Here we performed genome-wide association studies (GWAS) of 101 …
related complex traits. Here we performed genome-wide association studies (GWAS) of 101 …
Multivariate genetic analysis of personality and cognitive traits reveals abundant pleiotropy
G Hindley, AA Shadrin, D van der Meer… - Nature human …, 2023 - nature.com
Personality and cognitive function are heritable mental traits whose genetic foundations may
be distributed across interconnected brain functions. Previous studies have typically treated …
be distributed across interconnected brain functions. Previous studies have typically treated …
Common genetic variation influencing human white matter microstructure
INTRODUCTION White matter in the human brain serves a critical role in organizing
distributed neural networks. Diffusion magnetic resonance imaging (dMRI) has enabled the …
distributed neural networks. Diffusion magnetic resonance imaging (dMRI) has enabled the …
Long-term cannabis use and cognitive reserves and hippocampal volume in midlife
Objective: Cannabis use is increasing among midlife and older adults. This study tested the
hypotheses that long-term cannabis use is associated with cognitive deficits and smaller …
hypotheses that long-term cannabis use is associated with cognitive deficits and smaller …
FreeSurfer‐based segmentation of hippocampal subfields: A review of methods and applications, with a novel quality control procedure for ENIGMA studies and other …
PG Sämann, JE Iglesias, B Gutman… - Human brain …, 2022 - Wiley Online Library
Structural hippocampal abnormalities are common in many neurological and psychiatric
disorders, and variation in hippocampal measures is related to cognitive performance and …
disorders, and variation in hippocampal measures is related to cognitive performance and …
Genetic association between schizophrenia and cortical brain surface area and thickness
Importance Schizophrenia is a complex heritable disorder associated with many genetic
variants, each with a small effect. While cortical differences between patients with …
variants, each with a small effect. While cortical differences between patients with …
[HTML][HTML] The interactions between host genome and gut microbiome increase the risk of psychiatric disorders: Mendelian randomization and biological annotation
L Xiao, S Liu, Y Wu, Y Huang, S Tao, Y Liu… - Brain, behavior, and …, 2023 - Elsevier
Background The correlation between human gut microbiota and psychiatric diseases has
long been recognized. Based on the heritability of the microbiome, genome-wide …
long been recognized. Based on the heritability of the microbiome, genome-wide …