X-linked hypophosphataemia (XLH) is the most common cause of inherited phosphate
wasting and is associated with severe complications such as rickets, lower limb deformities …

Rickets is a bone disease associated with abnormal serum calcium and phosphate levels.
The clinical presentation is heterogeneous and depends on the age of onset and …

Objective Hereditary hypophosphatemias (HH) are rare monogenic conditions characterized
by decreased renal tubular phosphate reabsorption. The aim of this study was to explore the …

Abstract X‐linked hypophosphatemia (XLH), characterized by renal phosphate wasting, is
the most common cause of vitamin D‐resistant rickets. It has been postulated that some …

Rickets is a disease of the growing child arising from alterations in calcium and phosphate
homeostasis resulting in impaired apoptosis of hypertrophic chondrocytes in the growth …

The phosphatonin pathway: New insights in phosphate homeostasis. Serum phosphate
concentrations are maintained within a defined range by processes that regulate the …

Phosphate homeostasis is central to diverse physiologic processes including energy
homeostasis, formation of lipid bilayers, and bone formation. Reduced phosphate levels due …

Early diagnosis, optimal therapeutic management and regular follow up of children with X-
linked hypophosphatemia (XLH) determine their long term outcomes and future quality of …

Abstract X‐linked hypophosphatemia (XLH), the most common form of hereditary
hypophosphatemia, is caused by disrupting variants in the PHEX gene, located on the X …

Hypophosphatemic rickets (HR) is a group of rare disorders caused by excessive renal
phosphate wasting. The purpose of this cross-sectional study of 38 HR patients was to …