Background The growing body of evidence indicating the heterogeneity of Alzheimer's
disease (AD), coupled with disappointing clinical studies directed at a fit-for-all therapy …

An estimated 47 million people worldwide are living with dementia in 2015, and this number
is projected to triple by 2050. In the absence of a disease-modifying treatment or cure …

Background The number of individuals living with dementia is increasing, negatively
affecting families, communities, and health-care systems around the world. A successful …

Background Traumatic brain injury (TBI) and spinal cord injury (SCI) are increasingly
recognised as global health priorities in view of the preventability of most injuries and the …

Purpose We aimed to quantify the relative risk of progression from mild cognitive impairment
(MCI) to dementia in people with and without diabetes, and with and without the MetS …

Objective: Public health campaigns encouraging early help seeking have increased rates of
mild cognitive impairment (MCI) diagnosis in Western countries, but we know little about …

A systematic review was conducted to identify risk factors associated with the onset and
progression of Alzheimer's disease (AD). Moderate and high quality systematic reviews …

Objective Dementia has a multifactorial etiology, but the importance of individual health and
lifestyle related risk factors is often uncertain or based on few studies. The goal of this paper …

Background: Cohort studies have reported that midlife high total serum cholesterol (TC) is
associated with increased risk of Alzheimer's disease (AD) in late-life but findings have been …

An estimated 24 million people worldwide have dementia, the majority of whom are thought
to have Alzheimer's disease. Thus, Alzheimer's disease represents a major public health …