Abstract Toll-like receptor (TLR) 4 belongs to the TLR family of receptors inducing pro-
inflammatory responses to invading pathogens. TLR4 is activated by lipopolysaccharide …

Biomaterials have had an increasingly important role in recent decades, in biomedical
device design and the development of tissue engineering solutions for cell delivery, drug …

Recognizing the importance of leukocyte trafficking in inflammation led to some therapeutic
breakthroughs. However, many inflammatory pathologies remain without specific therapy …

Idiopathic pulmonary fibrosis (IPF), the most common form of idiopathic interstitial
pneumonia, is a progressive, irreversible, and typically lethal disease characterized by an …

Abstract Toll-like receptor 4 (TLR4), a member of the Toll-like receptor (TLR) family, is
involved in innate immunity and mediates inflammatory responses by recognizing …

Trauma can affect any individual at any location and at any time over a lifespan. The
disruption of macrobarriers and microbarriers induces instant activation of innate immunity …

Hyaluronan (HA) is a linear nonsulfated glycosaminoglycan of the extracellular matrix that
plays a pivotal role in a variety of biological processes. High‐molecular weight HA exhibits …

Tissue damage and inflammation are important triggers for regeneration and fibrosis. Tissue
damage not only induces inflammation in general, it also determines the type and …

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are a continuum of
lung changes arising from a wide variety of lung injuries, frequently resulting in significant …

Inflammatory processes are firmly established as central to the development and
complications of cardiovascular diseases. Elevated levels of inflammatory markers have …