The neuroinflammatory hypothesis of delirium
J Cerejeira, H Firmino, A Vaz-Serra… - Acta …, 2010 - Springer
Delirium is a neuropsychiatric syndrome characterized by a sudden and global impairment
in consciousness, attention and cognition. It is particularly frequent in elderly subjects with …
in consciousness, attention and cognition. It is particularly frequent in elderly subjects with …
Drug-induced cognitive impairment in the elderly
AR Moore, ST O'Keeffe - Drugs & aging, 1999 - Springer
Elderly people are more likely than younger patients to develop cognitive impairment as a
result of taking medications. This reflects age-and disease-associated changes in brain …
result of taking medications. This reflects age-and disease-associated changes in brain …
Long-term postoperative cognitive dysfunction in the elderly: ISPOCD1 study
JT Moller, P Cluitmans, LS Rasmussen, P Houx… - The Lancet, 1998 - thelancet.com
Background Long-term postoperative cognitive dysfunction may occur in the elderly. Age
may be a risk factor and hypoxaemia and arterial hypotension causative factors. We …
may be a risk factor and hypoxaemia and arterial hypotension causative factors. We …
Anesthesia leads to tau hyperphosphorylation through inhibition of phosphatase activity by hypothermia
E Planel, KEG Richter, CE Nolan, JE Finley… - Journal of …, 2007 - Soc Neuroscience
Postoperative cognitive dysfunction, confusion, and delirium are common after general
anesthesia in the elderly, with symptoms persisting for months or years in some patients …
anesthesia in the elderly, with symptoms persisting for months or years in some patients …
The association between delirium and cognitive decline: a review of the empirical literature
JC Jackson, SM Gordon, RP Hart, RO Hopkins… - Neuropsychology …, 2004 - Springer
Delirium is a common neurobehavioral syndrome that occurs across health care settings
which is associated with adverse outcomes, including death. There are limited data on long …
which is associated with adverse outcomes, including death. There are limited data on long …
Ketamine attenuates delirium after cardiac surgery with cardiopulmonary bypass
JA Hudetz, KM Patterson, Z Iqbal, SD Gandhi… - Journal of cardiothoracic …, 2009 - Elsevier
OBJECTIVE: To determine if ketamine attenuates postoperative delirium concomitant with
an anti-inflammatory effect in patients undergoing cardiac surgery using cardiopulmonary …
an anti-inflammatory effect in patients undergoing cardiac surgery using cardiopulmonary …
Cognitive function after anaesthesia in the elderly
AY Bekker, EJ Weeks - Best Practice & Research Clinical Anaesthesiology, 2003 - Elsevier
Despite advances in peri operative care, a significant percentage of elderly patients
experience transient post operative delirium and/or long-term post-operative cognitive …
experience transient post operative delirium and/or long-term post-operative cognitive …
[HTML][HTML] Postoperative sleep disorders and their potential impacts on surgical outcomes
Postoperative sleep disturbance is a common occurrence with significant adverse effects on
patients including delayed recovery, impairment of cognitive function, pain sensitivity and …
patients including delayed recovery, impairment of cognitive function, pain sensitivity and …
Acute confusional state in the elderly following hip surgery: incidence, risk factors and complications
P Galanakis, H Bickel, R Gradinger… - … journal of geriatric …, 2001 - Wiley Online Library
Objective To determine incidence and risk factors for the development of postoperative
acute confusional state (ACS) in the elderly. Design A prospective cohort study. Setting …
acute confusional state (ACS) in the elderly. Design A prospective cohort study. Setting …
[PDF][PDF] Increased incidence of postoperative cognitive dysfunction 24 hr after minor surgery in the elderly
D Rohan, DJ Buggy, S Crowley, FKH Ling… - Canadian Journal of …, 2005 - researchgate.net
Purpose: Postoperative cognitive dysfunction (POCD) is evident in 26% of elderly patients
seven days after major non-cardiac surgery. Despite the growing popularity of day surgery …
seven days after major non-cardiac surgery. Despite the growing popularity of day surgery …