Genetic predisposition to multiple sclerosis (MS) only explains a fraction of the disease risk;
lifestyle and environmental factors are key contributors to the risk of MS. Importantly, these …

Microfold (M) cells are located in the epithelium covering mucosa-associated lymphoid
tissues, such as the Peyer's patches (PPs) of the small intestine. M cells actively transport …

Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system
underpinned by partially understood genetic risk factors and environmental triggers and …

Multiple sclerosis (MS) is a common autoimmune disease that targets myelin in the central
nervous system (CNS). Multiple genome-wide association studies (GWAS) over the past 10 …

Neurodegenerative diseases of the central nervous system (CNS) are characterized by
progressive neuronal death and neurological dysfunction, leading to increased disability …

Lifestyle and environmental factors potently influence the risk of multiple sclerosis (MS),
because genetic predisposition only explains a fraction of the risk increase. There is strong …

Objective To quantify improvements in walking performance commonly observed in patients
with multiple sclerosis (pwMS), a systematic literature search and meta-analysis were …

The contribution of genetic inheritance in multiple sclerosis was established early on.
Although multiple sclerosis is not a Mendelian disease, its incidence and prevalence is …

Vitamin D deficiency has been associated with the risk of multiple sclerosis, disease activity
and progression. Results from in vitro experiments, animal models and analysis of human …

Large-scale mapping studies have identified 236 independent genetic variants associated
with an increased risk of multiple sclerosis. However, none of these variants are found …