Towards understanding the direct and indirect actions of growth hormone in controlling hepatocyte carbohydrate and lipid metabolism
MC Vázquez-Borrego, M del Rio-Moreno, RD Kineman - Cells, 2021 - mdpi.com
Growth hormone (GH) is critical for achieving normal structural growth. In addition, GH plays
an important role in regulating metabolic function. GH acts through its GH receptor (GHR) to …
an important role in regulating metabolic function. GH acts through its GH receptor (GHR) to …
Understanding the role of growth hormone in situations of metabolic stress
Growth hormone (GH) is secreted by the anterior pituitary gland and plays a key role in
controlling tissue and body growth. While basal GH secretion is considerably reduced along …
controlling tissue and body growth. While basal GH secretion is considerably reduced along …
Involvement of sirtuin 1 in the growth hormone/insulin-like growth factor 1 signal transduction and its impact on growth processes in children
A Fedorczak, A Lewiński, R Stawerska - International Journal of …, 2023 - mdpi.com
The regulation of growth processes in children depends on the synthesis of growth hormone
(GH) and insulin-like growth factor 1 (IGF-1). Insulin-like growth factor 1, which is mainly …
(GH) and insulin-like growth factor 1 (IGF-1). Insulin-like growth factor 1, which is mainly …
Fasting and prolonged food restriction differentially affect GH secretion independently of GH receptor signaling in AgRP neurons
ME de Sousa, DO Gusmao… - Journal of …, 2023 - Wiley Online Library
Growth hormone (GH) receptor (GHR) is abundantly expressed in neurons that co‐release
the agouti‐related protein (AgRP) and neuropeptide Y (NPY) in the arcuate nucleus of the …
the agouti‐related protein (AgRP) and neuropeptide Y (NPY) in the arcuate nucleus of the …
Sexual dimorphism in the molecular mechanisms of insulin resistance during a critical developmental window in Wistar rats
Background Insulin resistance (IR) is a condition in which the response of organs to insulin
is impaired. IR is an early marker of metabolic dysfunction. However, IR also appears in …
is impaired. IR is an early marker of metabolic dysfunction. However, IR also appears in …
Growth hormone receptor (GHR) in AgRP neurons regulates thermogenesis in a sex-specific manner
Evidence for hypothalamic regulation of energy homeostasis and thermoregulation in brown
adipose tissue (BAT) during aging has been well recognized, yet the central molecular …
adipose tissue (BAT) during aging has been well recognized, yet the central molecular …
Insulin-like Growth Factor 1, Growth Hormone, and Anti-Müllerian Hormone Receptors Are Differentially Expressed during GnRH Neuron Development
AJJ Paganoni, R Cannarella, R Oleari… - International Journal of …, 2023 - mdpi.com
Gonadotropin-releasing hormone (GnRH) neurons are key neuroendocrine cells in the brain
as they control reproduction by regulating hypothalamic-pituitary-gonadal axis function. In …
as they control reproduction by regulating hypothalamic-pituitary-gonadal axis function. In …
The Multiple Faces of the GH/IGF Axis
V Chesnokova - Cells, 2022 - mdpi.com
Over the past two decades, interest in the role of the somatotroph growth
hormone/insulinlike growth factor (GH/IGF1) axis in multiple aspects of physiology and …
hormone/insulinlike growth factor (GH/IGF1) axis in multiple aspects of physiology and …
Sirtuin 1 serum concentration in healthy children-dependence on sex, age, stage of puberty, body weight and diet
A Fedorczak, A Lewiński, R Stawerska - Frontiers in Endocrinology, 2024 - frontiersin.org
Introduction Sirtuin 1 (SIRT1) is known to be involved in sensing cellular energy levels and
regulating energy metabolism. This study aimed to evaluate fasting serum SIRT1 levels in …
regulating energy metabolism. This study aimed to evaluate fasting serum SIRT1 levels in …