Structure and assembly of the nuclear pore complex
B Hampoelz, A Andres-Pons… - Annual review of …, 2019 - annualreviews.org
Nuclear pore complexes (NPCs) mediate nucleocytoplasmic exchange. They are
exceptionally large protein complexes that fuse the inner and outer nuclear membranes to …
exceptionally large protein complexes that fuse the inner and outer nuclear membranes to …
Orchestrating nuclear envelope disassembly and reassembly during mitosis
S Güttinger, E Laurell, U Kutay - Nature reviews Molecular cell biology, 2009 - nature.com
Cell division in eukaryotes requires extensive architectural changes of the nuclear envelope
(NE) to ensure that segregated DNA is finally enclosed in a single cell nucleus in each …
(NE) to ensure that segregated DNA is finally enclosed in a single cell nucleus in each …
The nuclear envelope
MW Hetzer - Cold Spring Harbor perspectives in biology, 2010 - cshperspectives.cshlp.org
The nuclear envelope (NE) is a highly regulated membrane barrier that separates the
nucleus from the cytoplasm in eukaryotic cells. It contains a large number of different …
nucleus from the cytoplasm in eukaryotic cells. It contains a large number of different …
Spatial and temporal coordination of mitosis by Ran GTPase
PR Clarke, C Zhang - Nature reviews Molecular cell biology, 2008 - nature.com
Abstract The small nuclear GTPase Ran controls the directionality of macromolecular
transport between the nucleus and the cytoplasm. Ran also has important roles during …
transport between the nucleus and the cytoplasm. Ran also has important roles during …
Structure, dynamics and function of nuclear pore complexes
MA D'Angelo, MW Hetzer - Trends in cell biology, 2008 - cell.com
Nuclear pore complexes are large aqueous channels that penetrate the nuclear envelope,
thereby connecting the nuclear interior with the cytoplasm. Until recently, these …
thereby connecting the nuclear interior with the cytoplasm. Until recently, these …
ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division
Nuclear pores span the nuclear envelope and act as gated aqueous channels to regulate
the transport of macromolecules between the nucleus and cytoplasm, from individual …
the transport of macromolecules between the nucleus and cytoplasm, from individual …
Nuclear pore proteins and the control of genome functions
A Ibarra, MW Hetzer - Genes & development, 2015 - genesdev.cshlp.org
Nuclear pore complexes (NPCs) are composed of several copies of∼ 30 different proteins
called nucleoporins (Nups). NPCs penetrate the nuclear envelope (NE) and regulate the …
called nucleoporins (Nups). NPCs penetrate the nuclear envelope (NE) and regulate the …
Systematic kinetic analysis of mitotic dis-and reassembly of the nuclear pore in living cells
During mitosis in higher eukaryotes, nuclear pore complexes (NPCs) disassemble in
prophase and are rebuilt in anaphase and telophase. NPC formation is hypothesized to …
prophase and are rebuilt in anaphase and telophase. NPC formation is hypothesized to …
Repo-Man coordinates chromosomal reorganization with nuclear envelope reassembly during mitotic exit
Repo-Man targets protein phosphatase 1 γ (PP1γ) to chromatin at anaphase onset and
regulates chromosome structure during mitotic exit. Here, we show that a Repo-Man: PP1 …
regulates chromosome structure during mitotic exit. Here, we show that a Repo-Man: PP1 …
MEL‐28/ELYS is required for the recruitment of nucleoporins to chromatin and postmitotic nuclear pore complex assembly
C Franz, R Walczak, S Yavuz, R Santarella… - EMBO …, 2007 - embopress.org
The metazoan nuclear envelope (NE) breaks down and re‐forms during each cell cycle.
Nuclear pore complexes (NPCs), which allow nucleocytoplasmic transport during …
Nuclear pore complexes (NPCs), which allow nucleocytoplasmic transport during …