Diabetes mellitus has profound effects on multiple organ systems; however, the loss of
vision caused by diabetic retinopathy might be one of the most impactful in a patient's life …

Primary percutaneous coronary intervention (PCI) is the best available reperfusion strategy
for acute ST-segment elevation myocardial infarction (STEMI), with nearly 95% of occluded …

Owing to its high disability and mortality rates, stroke has been the second leading cause of
death worldwide. Since the pathological mechanisms of stroke are not fully understood …

Objective We conducted a Mendelian randomization (MR) study to disentangle the
comparative effects of lipids and apolipoproteins on ischemic stroke. Methods Single …

Blood brain barrier (BBB) injury is an important factor affecting the prognosis of ischemic
stroke. Extensive research on BBB injury has revealed that blood vessels and neural …

In patients with acute myocardial infarction (AMI), the guideline-recommended treatment is
mechanical revascularization by percutaneous coronary intervention (PCI), which is effective …

The majority of patients with diabetic macular edema (DME), the most common cause of
vision loss in working-age Americans, do not respond adequately to current therapies …

Impaired wound healing is a major source of morbidity in diabetic patients. Poor outcome
has, in part, been related to increased inflammation, poor angiogenesis, and deficiencies in …

Background Angptl4 is a secreted protein involved in the regulation of vascular permeability,
angiogenesis, and inflammatory responses in different kinds of tissues. Increases of …

Few intravenously administered mesenchymal stromal cells (MSCs) engraft to the injured
myocardium, thereby limiting their therapeutic efficacy for the treatment of ischemic heart …