Review of signaling pathways governing MSC osteogenic and adipogenic differentiation

AW James - Scientifica, 2013 - Wiley Online Library
Mesenchymal stem cells (MSC) are multipotent cells, functioning as precursors to a variety
of cell types including adipocytes, osteoblasts, and chondrocytes. Between osteogenic and …

Regulation of adipocyte lipolysis

G Frühbeck, L Méndez-Giménez… - Nutrition research …, 2014 - cambridge.org
In adipocytes the hydrolysis of TAG to produce fatty acids and glycerol under fasting
conditions or times of elevated energy demands is tightly regulated by neuroendocrine …

Causes and mechanisms of adipocyte enlargement and adipose expansion

F Haczeyni, KS Bell‐Anderson, GC Farrell - Obesity reviews, 2018 - Wiley Online Library
Adipose tissue plays a significant role in whole body energy homeostasis. Obesity‐
associated diabetes, fatty liver and metabolic syndrome are closely linked to adipose stress …

[HTML][HTML] Apigenin inhibits STAT3/CD36 signaling axis and reduces visceral obesity

T Su, C Huang, C Yang, T Jiang, J Su, M Chen… - Pharmacological …, 2020 - Elsevier
Visceral obesity is the excess deposition of visceral fat within the abdominal cavity that
surrounds vital organs. Visceral obesity is directly associated with metabolic syndrome …

Rodent models of nonalcoholic fatty liver disease

F Zhong, X Zhou, J Xu, L Gao - Digestion, 2020 - karger.com
Background: Nonalcoholic fatty liver disease (NAFLD) is a continuous diseases spectrum
associated with obesity, type 2 diabetes, insulin resistance, and hyperlipidemia. Simple …

[HTML][HTML] Fatty acid mobilization from adipose tissue is mediated by CD36 posttranslational modifications and intracellular trafficking

AC Daquinag, Z Gao, C Fussell, L Immaraj… - JCI insight, 2021 - ncbi.nlm.nih.gov
The mechanism controlling long-chain fatty acid (LCFA) mobilization from adipose tissue is
not well understood. Here, we investigated how the LCFA transporter CD36 regulates this …

Adipose morphology and metabolic disease

P Tandon, R Wafer… - Journal of Experimental …, 2018 - journals.biologists.com
Adipose morphology is defined as the number and size distribution of adipocytes (fat cells)
within adipose tissue. Adipose tissue with fewer but larger adipocytes is said to have a …

The multifunctionality of CD36 in diabetes mellitus and its complications—update in pathogenesis, treatment and monitoring

K Puchałowicz, ME Rać - Cells, 2020 - mdpi.com
CD36 is a multiligand receptor contributing to glucose and lipid metabolism, immune
response, inflammation, thrombosis, and fibrosis. A wide range of tissue expression includes …

Imidacloprid promotes high fat diet-induced adiposity and insulin resistance in male C57BL/6J mice

Q Sun, X Xiao, Y Kim, D Kim, KS Yoon… - Journal of agricultural …, 2016 - ACS Publications
Imidacloprid, a neonicotinoid insecticide widely used in agriculture worldwide, has been
reported to promote adipogenesis and cause insulin resistance in vitro. The purpose of the …

CD36 is a marker of human adipocyte progenitors with pronounced adipogenic and triglyceride accumulation potential

H Gao, F Volat, L Sandhow, J Galitzky, T Nguyen… - Stem …, 2017 - academic.oup.com
White adipose tissue (WAT) expands in part through adipogenesis, a process involving fat
cell generation and fatty acid (FA) storage into triglycerides (TGs). Several findings suggest …