Deconstructing a syndrome: genomic insights into PCOS causal mechanisms and classification

M Dapas, A Dunaif - Endocrine reviews, 2022 - academic.oup.com
Polycystic ovary syndrome (PCOS) is among the most common disorders in women of
reproductive age, affecting up to 15% worldwide, depending on the diagnostic criteria …

Genomics of local adaptation with gene flow

A Tigano, VL Friesen - Molecular ecology, 2016 - Wiley Online Library
Gene flow is a fundamental evolutionary force in adaptation that is especially important to
understand as humans are rapidly changing both the natural environment and natural levels …

[图书][B] Eco-evolutionary dynamics

AP Hendry - 2017 - degruyter.com
In recent years, scientists have realized that evolution can occur on timescales much shorter
than the" long lapse of ages" emphasized by Darwin—in fact, evolutionary change is …

[图书][B] Ecological speciation

P Nosil - 2012 - books.google.com
The origin of biological diversity, via the formation of new species, can be inextricably linked
to adaptation to the ecological environment. Specifically, ecological processes are central to …

Microgeographic adaptation and the spatial scale of evolution

JL Richardson, MC Urban, DI Bolnick… - Trends in ecology & …, 2014 - cell.com
Local adaptation has been a major focus of evolutionary ecologists working across diverse
systems for decades. However, little of this research has explored variation at …

What Is Ne, Anyway?

RS Waples - Journal of Heredity, 2022 - academic.oup.com
Few doubt that effective population size (N e) is one of the most important parameters in
evolutionary biology, but how many can say they really understand the concept? N e is the …

Conceptual issues in local adaptation

TJ Kawecki, D Ebert - Ecology letters, 2004 - Wiley Online Library
Studies of local adaptation provide important insights into the power of natural selection
relative to gene flow and other evolutionary forces. They are a paradigm for testing …

Analysis of hybrid zones

NH Barton, GM Hewitt - Annual review of Ecology and Systematics, 1985 - JSTOR
Hybrid zones are, roughly speaking, narrow regions in which genetically distinct populations
meet, mate, and produce hybrids. They are often only a few hundred meters wide and yet …

The evolution of ecological specialization

DJ Futuyma, G Moreno - Annual review of Ecology and Systematics, 1988 - JSTOR
The evolution of" niche breadth," or" niche width," was a more popular topic in the
evolutionary ecological literature of the 1960s and 1970s than it has been recently (109 …

Local adaptation by alleles of small effect

S Yeaman - The American Naturalist, 2015 - journals.uchicago.edu
Population genetic models predict that alleles with small selection coefficients may be
swamped by migration and will not contribute to local adaptation. But if most alleles …