RNA adopts 3D structures that confer varied functional roles in human biology and
dysfunction in disease. Approaches to therapeutically target RNA structures with small …

Copper (I)-catalyzed 1, 3-dipolar cycloaddition between organic azides and terminal
alkynes, commonly known as CuAAC or click chemistry, has been identified as one of the …

Cu (I)-catalyzed azide–alkyne 1, 3-dipolar cycloaddition (CuAAC), popularly known as the
“click reaction”, serves as the most potent and highly dependable tool for facile construction …

The Huisgen 1, 3-dipolar cycloaddition reaction of organic azides and alkynes1, 2 has
gained considerable attention in recent years due to the introduction in 2001 of Cu (1) …

Since the discovery of organic azides by Peter Grieß more than 140 years ago, numerous
syntheses of these energy‐rich molecules have been developed. In more recent times in …

The copper-catalyzed cycloaddition reaction between azides and alkynes functions
efficiently in aqueous solution in the presence of a tris (triazolyl) amine ligand. The process …

Polytriazolylamines were synthesized by the copper (I)-catalyzed ligation of azides and
alkynes. The C 3-symmetric derivative, TBTA, was shown to be a powerful stabilizing ligand …

CuI‐catalyzed alkyne–azide cycloaddition provides 1, 4‐disubstituted 1, 2, 3‐triazoles with
such efficiency and scope that the transformation has been described as “click” chemistry …

Copper toxicity is a critical issue in the development of copper-based catalysts for copper (I)-
catalyzed azide–alkyne cycloaddition (CuAAC) reactions for applications in living systems …

In recent years, a number of bioorthogonal reactions have been developed, exemplified by
click chemistry, that enable the efficient formation of a specific product, even within a highly …