Towards a unified understanding of lithium action in basic biology and its significance for applied biology

E Jakobsson, O Argüello-Miranda, SW Chiu… - The Journal of …, 2017 - Springer
Lithium has literally been everywhere forever, since it is one of the three elements created in
the Big Bang. Lithium concentration in rocks, soil, and fresh water is highly variable from …

Wnt signaling in neural crest ontogenesis and oncogenesis

Y Ji, H Hao, K Reynolds, M McMahon, CJ Zhou - Cells, 2019 - mdpi.com
Neural crest (NC) cells are a temporary population of multipotent stem cells that generate a
diverse array of cell types, including craniofacial bone and cartilage, smooth muscle cells …

Transcriptome 3′ end organization by PCF11 links alternative polyadenylation to formation and neuronal differentiation of neuroblastoma

A Ogorodnikov, M Levin, S Tattikota, S Tokalov… - Nature …, 2018 - nature.com
Diversification at the transcriptome 3′ end is an important and evolutionarily conserved
layer of gene regulation associated with differentiation and dedifferentiation processes …

Crosstalk of the Wnt/β-catenin signaling pathway in the induction of apoptosis on cancer cells

C Trejo-Solis, A Escamilla-Ramirez, D Jimenez-Farfan… - Pharmaceuticals, 2021 - mdpi.com
The Wnt/β-catenin signaling pathway plays a major role in cell survival and proliferation, as
well as in angiogenesis, migration, invasion, metastasis, and stem cell renewal in various …

[HTML][HTML] Neural crest and cancer: Divergent travelers on similar paths

KL Gallik, RW Treffy, LM Nacke, K Ahsan… - Mechanisms of …, 2017 - Elsevier
Neural crest cells are multipotent progenitors that dynamically interpret diverse
microenvironments to migrate significant distances as a loosely associated collective and …

Sea turtle fibropapilloma tumors share genomic drivers and therapeutic vulnerabilities with human cancers

DJ Duffy, C Schnitzler, L Karpinski, R Thomas… - Communications …, 2018 - nature.com
Wildlife populations are under intense anthropogenic pressures, with the geographic range
of many species shrinking, dramatic reductions in population numbers and undisturbed …

WNT signaling, the development of the sympathoadrenal–paraganglionic system and neuroblastoma

J Becker, J Wilting - Cellular and Molecular Life Sciences, 2018 - Springer
Neuroblastoma (NB) is a tumor of the sympathoadrenal system arising in children under 15
years of age. In Germany, NB accounts for 7% of childhood cancer cases, but 11% of cancer …

[HTML][HTML] Wnt signalling drives context-dependent differentiation or proliferation in neuroblastoma

M Szemes, A Greenhough, Z Melegh, S Malik, A Yuksel… - Neoplasia, 2018 - Elsevier
Neuroblastoma is one of the commonest and deadliest solid tumours of childhood, and is
thought to result from disrupted differentiation of the developing sympathoadrenergic …

Neural crest cells development and neuroblastoma progression: Role of Wnt signaling

MH Ahmad, B Ghosh, MA Rizvi, M Ali… - Journal of Cellular …, 2023 - Wiley Online Library
Neuroblastoma (NB) is one of the most common heterogeneous extracranial cancers in
infancy that arises from neural crest (NC) cells of the sympathetic nervous system. The Wnt …

Retinoic acid and TGF-β signalling cooperate to overcome MYCN-induced retinoid resistance

DJ Duffy, A Krstic, M Halasz, T Schwarzl, A Konietzny… - Genome medicine, 2017 - Springer
Background Retinoid therapy is widely employed in clinical oncology to differentiate
malignant cells into their more benign counterparts. However, certain high-risk cohorts, such …