Quorum sensing in fungal species

X Tian, H Ding, W Ke, L Wang - Annual Review of Microbiology, 2021 - annualreviews.org
Quorum sensing (QS) is one of the most studied cell-cell communication mechanisms in
fungi. Research in the last 20 years has explored various fungal QS systems that are …

[HTML][HTML] Advances in understanding the evolution of fungal genome architecture

SJ Priest, V Yadav, J Heitman - F1000Research, 2020 - ncbi.nlm.nih.gov
Diversity within the fungal kingdom is evident from the wide range of morphologies fungi
display as well as the various ecological roles and industrial purposes they serve …

Cryptococcus neoformans: Sex, morphogenesis, and virulence

Y Zhao, X Lin - Infection, Genetics and Evolution, 2021 - Elsevier
Cryptococcus neoformans is a dimorphic fungus that causes lethal meningoencephalitis
mainly in immunocompromised individuals. Different morphotypes enable this …

Vaccination with a ZNF2oe Strain of Cryptococcus Provides Long-Lasting Protection against Cryptococcosis and Is Effective in Immunocompromised Hosts

T Pham, Y Li, W Watford, X Lin - Infection and Immunity, 2023 - Am Soc Microbiol
Systemic cryptococcosis is fatal without treatment. Even with the current antifungal therapies,
this disease kills 180,000 of 225,000 infected people annually. Exposure to the causative …

Discovery of CO2 tolerance genes associated with virulence in the fungal pathogen Cryptococcus neoformans

BJ Chadwick, LC Ristow, X Xie, DJ Krysan, X Lin - Nature microbiology, 2024 - nature.com
Cryptococcus neoformans is a ubiquitous soil fungus and airborne pathogen that causes
over 180,000 deaths each year. Cryptococcus must adapt to host CO2 levels to cause …

Genome evolution of asexual organisms and the paradox of sex in eukaryotes

E Hörandl, J Bast, A Brandt, S Scheu… - Evolutionary biology—A …, 2020 - Springer
The predominance of sex in eukaryotes is still enigmatic. Sex, a composed process of
meiosis and mixis cycles, confers high costs but the selective advantages remain unclear. In …

Immunoprotection against cryptococcosis offered by znf2 depends on capsule and the hyphal morphology

J Lin, T Pham, K Hipsher, N Glueck, Y Fan, X Lin - MBio, 2022 - Am Soc Microbiol
Systemic cryptococcosis is fatal without treatment. Globally, this disease kills 180,000 of the
225,000 infected people each year, even with the use of antifungal therapies. Currently …

The RAM signaling pathway links morphology, thermotolerance, and CO2 tolerance in the global fungal pathogen Cryptococcus neoformans

BJ Chadwick, T Pham, X Xie, LC Ristow, DJ Krysan… - Elife, 2022 - elifesciences.org
The environmental pathogen Cryptococcus neoformans claims over 180,000 lives each
year. Survival of this basidiomycete at host CO 2 concentrations has only recently been …

The role of REC8 in the innate immune response to viral infection

S Chen, Q Liu, L Zhang, J Ma, B Xue, H Li… - Journal of …, 2022 - Am Soc Microbiol
ABSTRACT REC8 meiotic recombination protein (REC8) is a member of structural
maintenance of chromosome (SMC) protein partners, which play an important role in …

The COMPASS Complex Regulates Fungal Development and Virulence through Histone Crosstalk in the Fungal Pathogen Cryptococcus neoformans

R Liu, X Chen, F Zhao, Y Jiang, Z Lu, H Ji, Y Feng, J Li… - Journal of Fungi, 2023 - mdpi.com
The Complex of Proteins Associated with Set1 (COMPASS) methylates lysine K4 on histone
H3 (H3K4) and is conserved from yeast to humans. Its subunits and regulatory roles in the …