Integrative regulation of human brain blood flow
Herein, we review mechanisms regulating cerebral blood flow (CBF), with specific focus on
humans. We revisit important concepts from the older literature and describe the interaction …
humans. We revisit important concepts from the older literature and describe the interaction …
Integration of cerebrovascular CO2 reactivity and chemoreflex control of breathing: mechanisms of regulation, measurement, and interpretation
PN Ainslie, J Duffin - American Journal of Physiology …, 2009 - journals.physiology.org
Cerebral blood flow (CBF) and its distribution are highly sensitive to changes in the partial
pressure of arterial CO2 (PaCO2). This physiological response, termed cerebrovascular …
pressure of arterial CO2 (PaCO2). This physiological response, termed cerebrovascular …
Hypoxemia, oxygen content, and the regulation of cerebral blood flow
RL Hoiland, AR Bain, MG Rieger… - American Journal …, 2016 - journals.physiology.org
This review highlights the influence of oxygen (O2) availability on cerebral blood flow (CBF).
Evidence for reductions in O2 content (CaO2) rather than arterial O2 tension (PaO2) as the …
Evidence for reductions in O2 content (CaO2) rather than arterial O2 tension (PaO2) as the …
The cerebral effects of ascent to high altitudes
Cellular hypoxia is the common final pathway of brain injury that occurs not just after
asphyxia, but also when cerebral perfusion is impaired directly (eg, embolic stroke) or …
asphyxia, but also when cerebral perfusion is impaired directly (eg, embolic stroke) or …
The ventilatory response to hypoxia in mammals: mechanisms, measurement, and analysis
LJ Teppema, A Dahan - Physiological reviews, 2010 - journals.physiology.org
The respiratory response to hypoxia in mammals develops from an inhibition of breathing
movements in utero into a sustained increase in ventilation in the adult. This ventilatory …
movements in utero into a sustained increase in ventilation in the adult. This ventilatory …
The cerebrovascular response to carbon dioxide in humans
A Battisti‐Charbonney, J Fisher… - The Journal of …, 2011 - Wiley Online Library
Non‐technical summary Two mechanisms control brain blood flow by changing blood
vessel diameter: autoregulation maintains flow in the face of perfusion pressure changes …
vessel diameter: autoregulation maintains flow in the face of perfusion pressure changes …
Effect of altitude on the heart and the lungs
P Bärtsch, JSR Gibbs - Circulation, 2007 - Am Heart Assoc
The increase in heart rate is related to increased sympathetic activity and vagal withdrawal.
10 For a given level of exercise, heart rate is greater at altitude11 (Figure 2), although the …
10 For a given level of exercise, heart rate is greater at altitude11 (Figure 2), although the …
Regulation of cerebral blood flow during exercise
JS Querido, AW Sheel - Sports medicine, 2007 - Springer
Constant cerebral blood flow (CBF) is vital to human survival. Originally thought to receive
steady blood flow, the brain has shown to experience increases in blood flow during …
steady blood flow, the brain has shown to experience increases in blood flow during …
Aerobic exercise improves cognition and cerebrovascular regulation in older adults
Objective To test the hypothesis that aerobic exercise is associated with improvements in
cognition and cerebrovascular regulation, we enrolled 206 healthy low-active middle-aged …
cognition and cerebrovascular regulation, we enrolled 206 healthy low-active middle-aged …
Regulation of the cerebral circulation by arterial carbon dioxide
RL Hoiland, JA Fisher, PN Ainslie - Comprehensive Physiology, 2011 - Wiley Online Library
Intact, coordinated, and precisely regulated cerebrovascular responses are required for the
maintenance of cerebral metabolic homeostasis, adequate perfusion, oxygen delivery, and …
maintenance of cerebral metabolic homeostasis, adequate perfusion, oxygen delivery, and …