The mechanisms by which FOXP3+ T follicular regulatory (Tfr) cells simultaneously steer
antibody formation toward microbe or vaccine recognition and away from self-reactivity …

Common variable immunodeficiency (CVID) is a heterogenous disease category created to
distinguish late‐onset antibody deficiencies from early‐onset diseases like …

Host genetic factors significantly influence susceptibility to SARS-CoV-2 infection and
COVID-19 severity. Among these genetic factors are single-nucleotide variants (SNVs) …

Long noncoding RNAs (lncRNA) play an important role in gene regulation and contribute to
tumorigenesis. While pan-cancer studies of lncRNA expression have been performed for …

The differentiation of naive and memory B cells into antibody-secreting cells (ASCs) is a key
feature of adaptive immunity. The requirement for phosphoinositide 3-kinase-delta (PI3Kδ) …

Background Carpal tunnel syndrome (CTS) is a common disorder caused by compression of
the median nerve in the wrist, resulting in pain and numbness throughout the hand and …

The prevalence of childhood obesity is increasing worldwide, along with the associated
common comorbidities of type 2 diabetes and cardiovascular disease in later life. Motivated …

The lifespan of double-positive (DP) thymocytes is critical for intrathymic development and
shaping the peripheral T cell repertoire. However, the molecular mechanisms that control …

Introduction Viral infections have been implicated as a risk factor for laryngeal cancer. Given
the possible effects of Corona virus disease 2019 (COVID-19) on the laryngeal tissue, we …

The ch12q13 locus is among the most significant childhood obesity loci identified in genome-
wide association studies. This locus resides in a non-coding region within FAIM2; thus, the …