IL-6 is involved both in immune responses and in inflammation, hematopoiesis, bone
metabolism and embryonic development. IL-6 plays roles in chronic inflammation (closely …

Hypertension is a highly prevalent condition with numerous health risks, and the incidence
of hypertension is greatest among older adults. Traditional discussions of hypertension have …

Chronic inflammation represents one of the most consistent biologic features of aging.
However, the precise etiology of persistent low-grade increases in inflammation remains …

Inflammation is a physiological process that repairs tissues in response to endogenous or
exogenous aggressions. Nevertheless, a chronic state of inflammation may have detrimental …

Skeletal muscle satellite cells are considered to play a crucial role in muscle fiber
maintenance, repair and remodeling. Our knowledge of the role of satellite cells in muscle …

Ageing is correlated with elevated bladder cancer incidence, morbidity and mortality.
Advanced age is also associated with elevated markers of chronic inflammation and …

Over the past two decades it became evident that the immune system plays a central role in
modulating learning, memory and neural plasticity. Under normal quiescent conditions …

Skeletal muscle has recently been identified as an endocrine organ. It has, therefore, been
suggested that cytokines and other peptides that are produced, expressed, and released by …

PURPOSE: To review findings from major epidemiologic studies regarding risk factors for
and consequences of elevated markers of inflammation in older adults. RESULTS: Most …

Over the past two decades our view of adipose tissue has undergone a dramatic change
from an inert energy storage tissue to an active endocrine organ. Adipose tissue …