[HTML][HTML] Circulating tumor cell isolation for cancer diagnosis and prognosis

Z Deng, S Wu, Y Wang, D Shi - EBioMedicine, 2022 - thelancet.com
Circulating tumor cells (CTCs) are tumor cells that shed from the primary tumor and
intravasate into the peripheral blood circulation system responsible for metastasis. Sensitive …

[HTML][HTML] Potential clinical utility of liquid biopsies in ovarian cancer

JW Zhu, P Charkhchi, MR Akbari - Molecular cancer, 2022 - Springer
Background Ovarian cancer (OC) is the most lethal gynecologic malignancy worldwide. One
of the main challenges in the management of OC is the late clinical presentation of disease …

Integrating liquid biopsies into the management of cancer

G Siravegna, S Marsoni, S Siena… - Nature reviews Clinical …, 2017 - nature.com
During cancer progression and treatment, multiple subclonal populations of tumour cells
compete with one another, with selective pressures leading to the emergence of …

[HTML][HTML] Emerging role of tumor cell plasticity in modifying therapeutic response

S Qin, J Jiang, Y Lu, EC Nice, C Huang… - Signal transduction and …, 2020 - nature.com
Resistance to cancer therapy is a major barrier to cancer management. Conventional views
have proposed that acquisition of resistance may result from genetic mutations. However …

Nanoparticle-based immunochemical biosensors and assays: recent advances and challenges

Z Farka, T Jurik, D Kovar, L Trnkova… - Chemical reviews, 2017 - ACS Publications
We review the progress achieved during the recent five years in immunochemical
biosensors (immunosensors) combined with nanoparticles for enhanced sensitivity. The …

[HTML][HTML] A review of circulating tumour cell enrichment technologies

AJ Rushton, G Nteliopoulos, JA Shaw, RC Coombes - Cancers, 2021 - mdpi.com
Simple Summary Circulating tumour cells (CTCs) are cancer cells shed into the bloodstream
from tumours and their analysis can provide important insights into cancer detection and …

The lipogenic regulator SREBP2 induces transferrin in circulating melanoma cells and suppresses ferroptosis

X Hong, W Roh, RJ Sullivan, KHK Wong, BS Wittner… - Cancer discovery, 2021 - AACR
Circulating tumor cells (CTC) are shed by cancer into the bloodstream, where a viable
subset overcomes oxidative stress to initiate metastasis. We show that single CTCs from …

[HTML][HTML] Applications of Raman spectroscopy in cancer diagnosis

GW Auner, SK Koya, C Huang, B Broadbent… - Cancer and Metastasis …, 2018 - Springer
Novel approaches toward understanding the evolution of disease can lead to the discovery
of biomarkers that will enable better management of disease progression and improve …

Homophilic CD44 interactions mediate tumor cell aggregation and polyclonal metastasis in patient-derived breast cancer models

X Liu, R Taftaf, M Kawaguchi, YF Chang, W Chen… - Cancer discovery, 2019 - AACR
Circulating tumor cells (CTC) seed cancer metastases; however, the underlying cellular and
molecular mechanisms remain unclear. CTC clusters were less frequently detected but more …

Nanoparticle probes for the detection of cancer biomarkers, cells, and tissues by fluorescence

AB Chinen, CM Guan, JR Ferrer, SN Barnaby… - Chemical …, 2015 - ACS Publications
Cancer is the second most common cause of death in the United States, trailing only heart
disease in incidence. Despite significant worldwide investment in research, cancer remains …