[HTML][HTML] Circulating tumor cell isolation for cancer diagnosis and prognosis
Circulating tumor cells (CTCs) are tumor cells that shed from the primary tumor and
intravasate into the peripheral blood circulation system responsible for metastasis. Sensitive …
intravasate into the peripheral blood circulation system responsible for metastasis. Sensitive …
[HTML][HTML] Potential clinical utility of liquid biopsies in ovarian cancer
JW Zhu, P Charkhchi, MR Akbari - Molecular cancer, 2022 - Springer
Background Ovarian cancer (OC) is the most lethal gynecologic malignancy worldwide. One
of the main challenges in the management of OC is the late clinical presentation of disease …
of the main challenges in the management of OC is the late clinical presentation of disease …
Integrating liquid biopsies into the management of cancer
During cancer progression and treatment, multiple subclonal populations of tumour cells
compete with one another, with selective pressures leading to the emergence of …
compete with one another, with selective pressures leading to the emergence of …
[HTML][HTML] Emerging role of tumor cell plasticity in modifying therapeutic response
Resistance to cancer therapy is a major barrier to cancer management. Conventional views
have proposed that acquisition of resistance may result from genetic mutations. However …
have proposed that acquisition of resistance may result from genetic mutations. However …
Nanoparticle-based immunochemical biosensors and assays: recent advances and challenges
We review the progress achieved during the recent five years in immunochemical
biosensors (immunosensors) combined with nanoparticles for enhanced sensitivity. The …
biosensors (immunosensors) combined with nanoparticles for enhanced sensitivity. The …
[HTML][HTML] A review of circulating tumour cell enrichment technologies
AJ Rushton, G Nteliopoulos, JA Shaw, RC Coombes - Cancers, 2021 - mdpi.com
Simple Summary Circulating tumour cells (CTCs) are cancer cells shed into the bloodstream
from tumours and their analysis can provide important insights into cancer detection and …
from tumours and their analysis can provide important insights into cancer detection and …
The lipogenic regulator SREBP2 induces transferrin in circulating melanoma cells and suppresses ferroptosis
Circulating tumor cells (CTC) are shed by cancer into the bloodstream, where a viable
subset overcomes oxidative stress to initiate metastasis. We show that single CTCs from …
subset overcomes oxidative stress to initiate metastasis. We show that single CTCs from …
[HTML][HTML] Applications of Raman spectroscopy in cancer diagnosis
Novel approaches toward understanding the evolution of disease can lead to the discovery
of biomarkers that will enable better management of disease progression and improve …
of biomarkers that will enable better management of disease progression and improve …
Homophilic CD44 interactions mediate tumor cell aggregation and polyclonal metastasis in patient-derived breast cancer models
Circulating tumor cells (CTC) seed cancer metastases; however, the underlying cellular and
molecular mechanisms remain unclear. CTC clusters were less frequently detected but more …
molecular mechanisms remain unclear. CTC clusters were less frequently detected but more …
Nanoparticle probes for the detection of cancer biomarkers, cells, and tissues by fluorescence
AB Chinen, CM Guan, JR Ferrer, SN Barnaby… - Chemical …, 2015 - ACS Publications
Cancer is the second most common cause of death in the United States, trailing only heart
disease in incidence. Despite significant worldwide investment in research, cancer remains …
disease in incidence. Despite significant worldwide investment in research, cancer remains …