Abstract Context The European Association of Urology (EAU) has updated its guidelines on
sexual and reproductive health for 2021. Objective To present a summary of the 2021 …

We herein summarise the evidence concerning the impact of sperm DNA fragmentation in
various clinical infertility scenarios and the advances on sperm DNA fragmentation tests …

Reports of the increasing incidence of male infertility paired with decreasing semen quality
have triggered studies on the effects of lifestyle and environmental factors on the male …

BACKGROUND Infertility is a global public health issue, affecting 15% of all couples of
reproductive age. Male factors, including decreased semen quality, are responsible for …

Sperm DNA integrity is crucial for fertilization and development of healthy offspring. The
spermatozoon undergoes extensive molecular remodeling of its nucleus during later phases …

Sperm DNA damage is prevalent among infertile men and is known to influence natural
reproduction. However, the impact of sperm DNA damage on assisted reproduction …

Sperm DNA fragmentation (SDF) has been generally acknowledged as a valuable tool for
male fertility evaluation. While its detrimental implications on sperm function were …

Infertility affects approximately 15% of couples trying to conceive, and a male factor
contributes to roughly half of these cases. Oxidative stress (OS) has been identified as one …

Approximately 10 to 15% of couples are impacted by infertility. Recently, the pivotal role that
lifestyle factors play in the development of infertility has generated a considerable amount of …

Sperm DNA fragmentation has been associated with reduced fertilization rates, embryo
quality, pregnancy rates and increased miscarriage rates. Various methods exist to test …