The hematopoietic stem cell (HSC) niche commonly refers to the pairing of hematopoietic
and mesenchymal cell populations that regulate HSC self-renewal, differentiation, and …

Hypoxia is a physiological cue that impacts diverse physiological processes, including
energy metabolism, autophagy, cell motility, angiogenesis, and erythropoiesis. One of the …

The existence of a haematopoietic stem cell niche as a spatially confined regulatory entity
relies on the notion that haematopoietic stem and progenitor cells (HSPCs) are strategically …

Hematopoietic stem cells (HSCs) are sustained in a specific microenvironment known as the
stem cell niche. Mammalian HSCs are kept quiescent in the endosteal niche, a hypoxic zone …

Lineage-Specific Hematopoietic Growth Factors | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …

Progenitor cells that are the basis for all blood cell production share the bone marrow with
more mature elements of the adaptive immune system. Specialized niches within the bone …

Hematopoietic stem cell (HSC) transplantation can restore a new functional hematopoietic
system in recipients in cases where the system of the recipient is not functional or for …

Hematopoietic stem and progenitor cells (HSPCs) are exposed to low levels of oxygen in the
bone marrow niche, and hypoxia-inducible factors (HIFs) are the main regulators of cellular …

Hematopoietic stem cells (HSCs) are fundamental to the generation of the body's blood and
immune cells. They reside primarily within the bone marrow (BM) niche microenvironment …

Significance: The effect of redox signaling on hematopoietic stem cell (HSC) function is not
clearly understood. Recent Advances: A growing body of evidence suggests that adult HSCs …