[HTML][HTML] Virology and cell biology of the hepatitis C virus life cycle–An update
J Dubuisson, FL Cosset - Journal of hepatology, 2014 - Elsevier
Hepatitis C virus (HCV) is an important human pathogen that causes hepatitis, liver cirrhosis
and hepatocellular carcinoma. It imposes a serious problem to public health in the world as …
and hepatocellular carcinoma. It imposes a serious problem to public health in the world as …
Crosstalk between nucleocytoplasmic trafficking and the innate immune response to viral infection
The nuclear pore complex is the sole gateway connecting the nucleoplasm and cytoplasm.
In humans, the nuclear pore complex is one of the largest multiprotein assemblies in the cell …
In humans, the nuclear pore complex is one of the largest multiprotein assemblies in the cell …
The dengue virus NS5 protein intrudes in the cellular spliceosome and modulates splicing
FA De Maio, G Risso, NG Iglesias, P Shah… - PLoS …, 2016 - journals.plos.org
Dengue virus NS5 protein plays multiple functions in the cytoplasm of infected cells,
enabling viral RNA replication and counteracting host antiviral responses. Here, we …
enabling viral RNA replication and counteracting host antiviral responses. Here, we …
Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes
ZH Davis, E Verschueren, GM Jang, K Kleffman… - Molecular cell, 2015 - cell.com
Mapping host-pathogen interactions has proven instrumental for understanding how viruses
manipulate host machinery and how numerous cellular processes are regulated. DNA …
manipulate host machinery and how numerous cellular processes are regulated. DNA …
A structure-informed atlas of human-virus interactions
G Lasso, SV Mayer, ER Winkelmann, T Chu, O Elliot… - Cell, 2019 - cell.com
While knowledge of protein-protein interactions (PPIs) is critical for understanding virus-host
relationships, limitations on the scalability of high-throughput methods have hampered their …
relationships, limitations on the scalability of high-throughput methods have hampered their …
A combined proteomics/genomics approach links hepatitis C virus infection with nonsense-mediated mRNA decay
HR Ramage, GR Kumar, E Verschueren, JR Johnson… - Molecular cell, 2015 - cell.com
Hepatitis C virus (HCV) is a leading cause of liver disease, but insight into virus-host
interactions remains limited. We systematically used affinity purification/mass spectrometry …
interactions remains limited. We systematically used affinity purification/mass spectrometry …
Hepatitis C virus alters the morphology and function of peroxisomes
E Martin de Fourchambault, N Callens… - Frontiers in …, 2023 - frontiersin.org
Despite the introduction of effective treatments for hepatitis C in clinics, issues remain
regarding the liver disease induced by chronic hepatitis C virus (HCV) infection. HCV is …
regarding the liver disease induced by chronic hepatitis C virus (HCV) infection. HCV is …
Virus-host interactomics: new insights and opportunities for antiviral drug discovery
B De Chassey, L Meyniel-Schicklin, J Vonderscher… - Genome medicine, 2014 - Springer
The current therapeutic arsenal against viral infections remains limited, with often poor
efficacy and incomplete coverage, and appears inadequate to face the emergence of drug …
efficacy and incomplete coverage, and appears inadequate to face the emergence of drug …
Proteomic approaches to uncovering virus–host protein interactions during the progression of viral infection
KK Lum, IM Cristea - Expert review of proteomics, 2016 - Taylor & Francis
The integration of proteomic methods to virology has facilitated a significant breadth of
biological insight into mechanisms of virus replication, antiviral host responses and viral …
biological insight into mechanisms of virus replication, antiviral host responses and viral …
[HTML][HTML] Elucidation of host–pathogen protein–protein interactions to uncover mechanisms of host cell rewiring
C Nicod, A Banaei-Esfahani, BC Collins - Current opinion in microbiology, 2017 - Elsevier
Highlights•Bacterial pathogens rewire host proteomes to enable their replication and
spread.•Identifying host-pathogen protein interactions elucidates pathogenic …
spread.•Identifying host-pathogen protein interactions elucidates pathogenic …