Osteogenesis imperfecta (OI) is a monogenic bone fragility disorder that usually is caused
by mutations in one of the two genes coding for collagen type I alpha chains, COL1A1 or …

Abstract Context Atypical femur fractures (AFFs) are serious adverse events associated with
bisphosphonates and often show poor healing. Evidence acquisition We performed a …

Osteoporosis‐related fractures are undertreated, due in part to misinformation about
recommended approaches to patient care and discrepancies among treatment guidelines …

Osteoporosis is characterized by the loss of bone mass, deterioration of the bone
microarchitecture, and an increased risk of fractures; these later complications are …

Mini abstract This meta-analysis demonstrated that a greater prevalence of delayed union
and nonunion and a longer time to fracture healing in the group that did not receive TPTD …

Osteoporosis is a skeletal disorder with enhanced bone fragility, usually affecting the elderly.
It is very rare in children and young adults and the definition is not only based on a low BMD …

Abstract Purpose of Review Atypical femur fractures (AFFs) are rare subtrochanteric or
diaphyseal fractures regarded as side effects of bisphosphonates (BPs), possibly with a …

Context Prolonged bisphosphonate (BP) treatment for osteoporosis prevents hip and other
fractures but causes atypical femoral fractures (AFF). Objective To establish the relationship …

Genetic susceptibility, together with old age, female sex, and low bone mineral density
(BMD) are amongst the strongest determinants of fracture risk. Tmost recent large-scale …

Osteoporosis and resulting osteoporotic fractures are responsible for significant morbidity,
excess mortality, and health care costs in the developed world. Medical therapy for …