Image-based computational fluid dynamics modeling in realistic arterial geometries

DA Steinman - Annals of biomedical engineering, 2002 - Springer
Local hemodynamics are an important factor in atherosclerosis, from the development of
early lesions, to the assessment of stroke risk, to determining the ultimate fate of a mature …

Erythrocytes: oxygen sensors and modulators of vascular tone

ML Ellsworth, CG Ellis, D Goldman… - …, 2009 - journals.physiology.org
Through oxygen-dependent release of the vasodilator ATP, the mobile erythrocyte plays a
fundamental role in matching microvascular oxygen supply with local tissue oxygen …

The capillary bed offers the largest hemodynamic resistance to the cortical blood supply

IG Gould, P Tsai, D Kleinfeld… - Journal of Cerebral …, 2017 - journals.sagepub.com
The cortical angioarchitecture is a key factor in controlling cerebral blood flow and oxygen
metabolism. Difficulties in imaging the complex microanatomy of the cortex have so far …

A cellular automaton model for tumour growth in inhomogeneous environment

T Alarcón, HM Byrne, PK Maini - Journal of theoretical biology, 2003 - Elsevier
Most of the existing mathematical models for tumour growth and tumour-induced
angiogenesis neglect blood flow. This is an important factor on which both nutrient and …

Abnormalities of retinal microvascular structure and risk of mortality from ischemic heart disease and stroke

N Witt, TY Wong, AD Hughes, N Chaturvedi… - …, 2006 - Am Heart Assoc
Abnormalities of the retinal microcirculation are found in hypertension and diabetes and
predict cardiovascular mortality. This study examined the relationship between …

Quantification of retinal vessel tortuosity in diabetic retinopathy using optical coherence tomography angiography

H Lee, M Lee, H Chung, HC Kim - Retina, 2018 - journals.lww.com
Purpose: To investigate the association of vessel tortuosity with severity of diabetic
retinopathy (DR) using optical coherence tomography angiography. Methods: We …

A novel three-dimensional computer-assisted method for a quantitative study of microvascular networks of the human cerebral cortex

F Cassot, F Lauwers, C Fouard, S Prohaska… - …, 2006 - Taylor & Francis
Objective: Detailed information on microvascular network anatomy is a requirement for
understanding several aspects of microcirculation, including oxygen transport, distributions …

Targeted insult to subsurface cortical blood vessels using ultrashort laser pulses: three models of stroke

N Nishimura, CB Schaffer, B Friedman, PS Tsai… - Nature …, 2006 - nature.com
We present a method to produce vascular disruptions within rat brain parenchyma that
targets single microvessels. We used two-photon microscopy to image vascular architecture …

3D-printed fluidic networks as vasculature for engineered tissue

IS Kinstlinger, JS Miller - Lab on a Chip, 2016 - pubs.rsc.org
Fabrication of vascular networks within engineered tissue remains one of the greatest
challenges facing the fields of biomaterials and tissue engineering. Historically, the …

Green's function methods for analysis of oxygen delivery to tissue by microvascular networks

TW Secomb, R Hsu, EYH Park… - Annals of biomedical …, 2004 - Springer
Delivery of oxygen to tissue is an essential function of the circulatory system. The distance
that oxygen can diffuse into oxygen-consuming tissue is small, and so tissue oxygenation is …