Introduction Although genome-wide association studies have been conducted to investigate
genetic variation of lung tumorigenesis, little is known about gene-gene (G× G) interactions …

Background The tightly controlled balance between osteogenic and adipogenic
differentiation of human bone marrow-derived stromal cells (BMSCs) is critical to maintain …

Calretinin is a promising diagnostic biomarker for malignant mesothelioma (MM), but less is
known about its prognostic role. Our aim was to evaluate the association between serum …

By crossing septin7-floxed mice with Lyz2-Cre mice carrying the Cre recombinase inserted
in the Lysozyme-M (Lyz2) gene locus we aimed the specific deletion of septin7 in myeloid …

DNA methylation serves as a reversible and prognostic biomarker for oral squamous cell
carcinoma (OSCC) patients. It is unclear whether the effect of DNA methylation on OSCC …

Germline genetic variants, including single-nucleotide variants (SNVs) and copy number
variants (CNVs), account for interpatient heterogeneity. In the past several decades, genome …

Cuproptosis a novel copper-dependent cell death modality, plays a crucial part in the
oncogenesis, progression and prognosis of tumors. However, the relationships among DNA …

Background. Asbestos exposure is associated with different asbestos-related diseases,
including malignant mesothelioma (MM). MM diagnosis is confirmed with …

The majority of these existing prognostic models of head and neck squamous cell carcinoma
(HNSCC) have unsatisfactory prediction accuracy since they solely utilize demographic and …

Cancer is a multifactorial malignant disease driven by environmental exposure, genetic
polymorphism, somatic mutation events, and other downstream omics (Shen et al., 2021a; …