[HTML][HTML] Diverse roles of mitochondria in ischemic stroke

JL Yang, S Mukda, SD Chen - Redox biology, 2018 - Elsevier
Stroke is the leading cause of adult disability and mortality in most developing and
developed countries. The current best practices for patients with acute ischemic stroke …

Mitochondria as a therapeutic target for ischemic stroke

Z He, N Ning, Q Zhou, SE Khoshnam… - Free Radical Biology and …, 2020 - Elsevier
Stroke is the leading cause of death and physical disability worldwide. Mitochondrial
dysfunction has been considered as one of the hallmarks of ischemic stroke and contributes …

Mitochondrial dysfunction and oxidative stress in Parkinson's disease

SR Subramaniam, MF Chesselet - Progress in neurobiology, 2013 - Elsevier
Parkinson's disease (PD) is a movement disorder that is characterized by the progressive
degeneration of dopaminergic neurons in substantia nigra pars compacta resulting in …

[HTML][HTML] Oxidative stress in ischemia/reperfusion injuries following acute ischemic stroke

A Jurcau, AI Ardelean - Biomedicines, 2022 - mdpi.com
Recanalization therapy is increasingly used in the treatment of acute ischemic stroke.
However, in about one third of these patients, recanalization is followed by …

[HTML][HTML] Bioenergetic role of mitochondrial fusion and fission

B Westermann - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 2012 - Elsevier
Mitochondria are highly dynamic organelles. Frequent cycles of fusion and fission adapt the
morphology of the mitochondrial compartment to the metabolic needs of the cell …

Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells

H Otera, C Wang, MM Cleland, K Setoguchi… - Journal of Cell …, 2010 - rupress.org
The cytoplasmic dynamin-related guanosine triphosphatase Drp1 is recruited to
mitochondria and mediates mitochondrial fission. Although the mitochondrial outer …

[HTML][HTML] New insights into the function and regulation of mitochondrial fission

H Otera, N Ishihara, K Mihara - … et Biophysica Acta (BBA)-Molecular Cell …, 2013 - Elsevier
Mitochondrial morphology changes dynamically by coordinated fusion and fission and
cytoskeleton-based transport. Cycles of outer and inner membrane fusion and fission are …

[HTML][HTML] Insights into the pathogenesis of neurodegenerative diseases: Focus on mitochondrial dysfunction and oxidative stress

A Jurcau - International journal of molecular sciences, 2021 - mdpi.com
As the population ages, the incidence of neurodegenerative diseases is increasing. Due to
intensive research, important steps in the elucidation of pathogenetic cascades have been …

[HTML][HTML] Asymmetrically segregated mitochondria provide cellular memory of hematopoietic stem cell replicative history and drive HSC attrition

A Hinge, J He, J Bartram, J Javier, J Xu, E Fjellman… - Cell stem cell, 2020 - cell.com
The metabolic requirements of hematopoietic stem cells (HSCs) change with their cell cycle
activity. However, the underlying role of mitochondria remains ill-defined. Here we found …

Plant peroxisomes: biogenesis and function

J Hu, A Baker, B Bartel, N Linka, RT Mullen… - The Plant …, 2012 - academic.oup.com
Peroxisomes are eukaryotic organelles that are highly dynamic both in morphology and
metabolism. Plant peroxisomes are involved in numerous processes, including primary and …