[HTML][HTML] Cancer neuroscience: State of the field, emerging directions
The nervous system governs both ontogeny and oncology. Regulating organogenesis
during development, maintaining homeostasis, and promoting plasticity throughout life, the …
during development, maintaining homeostasis, and promoting plasticity throughout life, the …
[HTML][HTML] Tumor microenvironment: barrier or opportunity towards effective cancer therapy
Tumor microenvironment (TME) is a specialized ecosystem of host components, designed
by tumor cells for successful development and metastasis of tumor. With the advent of 3D …
by tumor cells for successful development and metastasis of tumor. With the advent of 3D …
Tumor abnormality-oriented nanomedicine design
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
Neuroimmune cardiovascular interfaces control atherosclerosis
SK Mohanta, L Peng, Y Li, S Lu, T Sun, L Carnevale… - Nature, 2022 - nature.com
Atherosclerotic plaques develop in the inner intimal layer of arteries and can cause heart
attacks and strokes. As plaques lack innervation, the effects of neuronal control on …
attacks and strokes. As plaques lack innervation, the effects of neuronal control on …
[HTML][HTML] The updated landscape of tumor microenvironment and drug repurposing
Accumulating evidence shows that cellular and acellular components in tumor
microenvironment (TME) can reprogram tumor initiation, growth, invasion, metastasis, and …
microenvironment (TME) can reprogram tumor initiation, growth, invasion, metastasis, and …
Stress and cancer: mechanisms, significance and future directions
A Eckerling, I Ricon-Becker, L Sorski… - Nature Reviews …, 2021 - nature.com
The notion that stress and cancer are interlinked has dominated lay discourse for decades.
More recent animal studies indicate that stress can substantially facilitate cancer …
More recent animal studies indicate that stress can substantially facilitate cancer …
[HTML][HTML] Aspects of the tumor microenvironment involved in immune resistance and drug resistance
K Khalaf, D Hana, JTT Chou, C Singh… - Frontiers in …, 2021 - frontiersin.org
The tumor microenvironment (TME) is a complex and ever-changing “rogue organ”
composed of its own blood supply, lymphatic and nervous systems, stroma, immune cells …
composed of its own blood supply, lymphatic and nervous systems, stroma, immune cells …
[HTML][HTML] Nociceptor neurons affect cancer immunosurveillance
Solid tumours are innervated by nerve fibres that arise from the autonomic and sensory
peripheral nervous systems,,,–. Whether the neo-innervation of tumours by pain-initiating …
peripheral nervous systems,,,–. Whether the neo-innervation of tumours by pain-initiating …
Cancer-derived exosomes: their role in cancer biology and biomarker development
VC Kok, CC Yu - International Journal of Nanomedicine, 2020 - Taylor & Francis
Exosomes are a subset of tiny extracellular vesicles manufactured by all cells and are
present in all body fluids. They are produced actively in tumor cells, which are released and …
present in all body fluids. They are produced actively in tumor cells, which are released and …