Significance: Fibroblasts play a critical role in normal wound healing. Various extracellular
matrix (ECM) components, including collagens, fibrin, fibronectin, proteoglycans …

Chronic kidney disease (CKD) is characterized by pathological accumulation of extracellular
matrix (ECM) proteins in renal structures. Tubulointerstitial fibrosis is observed in glomerular …

Two-dimensional nanomaterials, an ultrathin class of materials such as graphene,
nanoclays, transition metal dichalcogenides (TMDs), and transition metal oxides (TMOs) …

Background Hypertrophic scars (HS) generally occur after injury to the deep layers of the
dermis, resulting in functional deficiency for patients. Growing evidence has been identified …

Hypertrophic scars (HTS) are predominant diseases after burn and trauma, which cause
severe physiological and psychological problems. HTS have been researched for decades …

Hypertrophic scars represent the most common complication of skin injury and are caused
by excessive cutaneous wound healing characterized by hypervascularity and pathological …

Background The hypertrophic scar (HS) is a serious fibrotic skin condition and a major
clinical problem. Interleukin-10 (IL-10) has been identified as a prospective scar-improving …

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, irreversible interstitial lung
disease, with no effective cure. Polydatin is a resveratrol glucoside with strong antioxidant …

The SRC kinase family comprises non-receptor tyrosine kinases that are ubiquitously
expressed in all cell types. Although Src is reportedly activated in pulmonary and renal …

Significance: Damage-associated molecular patterns (DAMPs) and pathogen-associated
molecular patterns (PAMPs) emanate from burn-injured tissue and enter systemic …