Hepatitis E virus: advances and challenges
At least 20 million hepatitis E virus (HEV) infections occur annually, with> 3 million
symptomatic cases and∼ 60,000 fatalities. Hepatitis E is generally self-limiting, with a case …
symptomatic cases and∼ 60,000 fatalities. Hepatitis E is generally self-limiting, with a case …
Hepatitis E virus
SU Emerson, RH Purcell - Reviews in medical virology, 2003 - Wiley Online Library
Hepatitis E virus (HEV) is a positive‐stranded RNA virus with a 7.2 kb genome that is
capped and polyadenylated. The virus is currently unclassified: the organisation of the …
capped and polyadenylated. The virus is currently unclassified: the organisation of the …
Molecular virology of hepatitis E virus
This review details the molecular virology of the hepatitis E virus (HEV). While replicons and
in vitro infection systems have recently become available, a lot of information on HEV has …
in vitro infection systems have recently become available, a lot of information on HEV has …
Hepatitis C virus NS5A: tales of a promiscuous protein
A Macdonald, M Harris - Journal of General Virology, 2004 - microbiologyresearch.org
The non-structural 5A (NS5A) protein of hepatitis C virus (HCV) has been the subject of
intensive research over the last decade. It is generally accepted that NS5A is a pleiotropic …
intensive research over the last decade. It is generally accepted that NS5A is a pleiotropic …
Genetic variability and evolution of hepatitis E virus
H Okamoto - Virus research, 2007 - Elsevier
Hepatitis E virus (HEV) is the sole member of the genus Hepevirus in the family Hepeviridae.
HEV is transmitted primarily by the fecal–oral route, and water-borne epidemics are …
HEV is transmitted primarily by the fecal–oral route, and water-borne epidemics are …
Hepatitis E virus genome structure and replication strategy
Hepatitis E virus (HEV) possesses many of the features of other positive-stranded RNA
viruses but also adds HEV-specific nuances, making its virus–host interactions unique. Slow …
viruses but also adds HEV-specific nuances, making its virus–host interactions unique. Slow …
A bicistronic subgenomic mRNA encodes both the ORF2 and ORF3 proteins of hepatitis E virus
J Graff, U Torian, H Nguyen, SU Emerson - Journal of virology, 2006 - Am Soc Microbiol
Hepatitis E virus replicons containing the neomycin resistance gene expressed from open
reading frames (ORFs) 2 and 3 were transfected into Huh-7 cells, and stable cell lines …
reading frames (ORFs) 2 and 3 were transfected into Huh-7 cells, and stable cell lines …
Heparan sulfate proteoglycans are required for cellular binding of the hepatitis E virus ORF2 capsid protein and for viral infection
The hepatitis E virus (HEV), a nonenveloped RNA virus, is the causative agent of hepatitis E.
The mode by which HEV attaches to and enters into target cells for productive infection …
The mode by which HEV attaches to and enters into target cells for productive infection …
ORF3 protein of hepatitis E virus is essential for virion release from infected cells
K Yamada, M Takahashi, Y Hoshino… - Journal of General …, 2009 - microbiologyresearch.org
The function of the hepatitis E virus (HEV) open reading frame 3 (ORF3) protein remains
unclear. To elucidate the role of the ORF3 protein in the virus life cycle, an infectious cDNA …
unclear. To elucidate the role of the ORF3 protein in the virus life cycle, an infectious cDNA …
Hepatitis E virus
SK Panda, D Thakral, S Rehman - Reviews in medical virology, 2007 - Wiley Online Library
Hepatitis E virus (HEV) is the aetiological agent of non‐HAV enterically transmitted hepatitis.
It is the major cause of sporadic as well as epidemic hepatitis, which is no longer confined to …
It is the major cause of sporadic as well as epidemic hepatitis, which is no longer confined to …