Bone remodelling is a dynamic process required for the maintenance of bone architecture in
response to the changing mechanical needs. It is also a vital process during the repair of …

Bone tissue undergoes constant remodeling and healing when fracture happens, in order to
ensure its structural integrity. In order to better understand open biological and clinical …

Regenerative bone implants promote new bone formation and ideally degrade
simultaneously to osteogenesis. Although clinically established calcium phosphate bone …

The skeleton supports and confers structure to the whole body but several pathological and
traumatic conditions affect the bone tissue. Most of those pathological conditions are specific …

The design of bone substitutes involves the creation of a microenvironment supporting
molecular cross-talk between cells and scaffolds during tissue formation and remodelling …

Biophysical stimuli can mimic endogenous electric potentials and currents in the natural
bone to enhance tissue healing and reconstruction in diseased bone. However, little is …

Inhibiting osteoclasts and osteoclast precursors to reduce bone resorption is an important
strategy to treat osteoclast-related diseases, such as peri-prosthetic osteolysis. In this study …

Quantification of in vitro osteoclast cultures (eg cell number) often relies on manual counting
methods. These approaches are labour intensive, time consuming and result in substantial …

Musculoskeletal disorders (MSDs) are associated with pain and lead to reduced mobility
and quality of life for patients. Radon therapy is used as alternative or complementary to …

Stromal vascular fraction (SVF) is the primary isolate obtained after enzymatic digestion of
adipose tissue that contains various cell types. Its successful application for cell-based …