The autonomic nervous system and cardiac arrhythmias: current concepts and emerging therapies

N Herring, M Kalla, DJ Paterson - Nature Reviews Cardiology, 2019 - nature.com
Research into cardiac autonomic control has received great interest in the past 20 years,
and we are now at a critical juncture with regard to the clinical translation of the experimental …

Autonomic modulation for cardiovascular disease

J Hadaya, JL Ardell - Frontiers in physiology, 2020 - frontiersin.org
Dysfunction of the autonomic nervous system has been implicated in the pathogenesis of
cardiovascular disease, including congestive heart failure and cardiac arrhythmias. Despite …

The intrinsic cardiac nervous system and its role in cardiac pacemaking and conduction

L Fedele, T Brand - Journal of cardiovascular development and disease, 2020 - mdpi.com
The cardiac autonomic nervous system (CANS) plays a key role for the regulation of cardiac
activity with its dysregulation being involved in various heart diseases, such as cardiac …

Efficacy of stellate ganglion blockade in managing electrical storm: a systematic review

L Meng, CH Tseng, K Shivkumar, O Ajijola - JACC: Clinical …, 2017 - jacc.org
Objectives: The study sought to characterize the efficacy of stellate ganglion block (SGB) as
a treatment for electrical storm (ES). Background: The efficacy of percutaneous SGB for …

Defining the neural fulcrum for chronic vagus nerve stimulation: implications for integrated cardiac control

JL Ardell, H Nier, M Hammer… - The Journal of …, 2017 - Wiley Online Library
Key points The evoked cardiac response to bipolar cervical vagus nerve stimulation (VNS)
reflects a dynamic interaction between afferent mediated decreases in central …

Neuroscientific therapies for atrial fibrillation

P Hanna, E Buch, S Stavrakis, C Meyer… - Cardiovascular …, 2021 - academic.oup.com
The cardiac autonomic nervous system (ANS) plays an integral role in normal cardiac
physiology as well as in disease states that cause cardiac arrhythmias. The cardiac ANS …

The role of the autonomic nervous system in arrhythmias and sudden cardiac death

S Franciosi, FKG Perry, TM Roston, KR Armstrong… - Autonomic …, 2017 - Elsevier
The autonomic nervous system (ANS) is complex and plays an important role in cardiac
arrhythmia pathogenesis. A deeper understanding of the anatomy and development of the …

Electroceutical targeting of the autonomic nervous system

CC Horn, JL Ardell, LE Fisher - Physiology, 2019 - journals.physiology.org
Autonomic nerves are attractive targets for medical therapies using electroceutical devices
because of the potential for selective control and few side effects. These devices use novel …

Calcium-induced autonomic denervation in patients with post-operative atrial fibrillation

H Wang, Y Zhang, F Xin, H Jiang, D Tao, Y Jin… - Journal of the American …, 2021 - jacc.org
Background Post-operative atrial fibrillation (POAF) is associated with worse long-term
cardiovascular outcomes. Objectives This study hypothesized that injecting calcium chloride …

Autonomic nervous system and cardiac neuro-signaling pathway modulation in cardiovascular disorders and Alzheimer's disease

A Elia, S Fossati - Frontiers in Physiology, 2023 - frontiersin.org
The heart is a functional syncytium controlled by a delicate and sophisticated balance
ensured by the tight coordination of its several cell subpopulations. Accordingly …