Pharmacology and therapeutics of bronchodilators
M Cazzola, CP Page, L Calzetta, MG Matera - Pharmacological Reviews, 2012 - ASPET
Bronchodilators are central in the treatment of of airways disorders. They are the mainstay of
the current management of chronic obstructive pulmonary disease (COPD) and are critical in …
the current management of chronic obstructive pulmonary disease (COPD) and are critical in …
The scientific rationale for combining long-acting β2-agonists and muscarinic antagonists in COPD
M Cazzola, M Molimard - Pulmonary pharmacology & therapeutics, 2010 - Elsevier
Bronchodilators are the cornerstone of pharmacological management of COPD. For patients
whose conditions are not sufficiently controlled by monotherapy, combining bronchodilators …
whose conditions are not sufficiently controlled by monotherapy, combining bronchodilators …
[HTML][HTML] Combination bronchodilator therapy in the management of chronic obstructive pulmonary disease
DP Tashkin, GT Ferguson - Respiratory research, 2013 - Springer
Chronic obstructive pulmonary disease (COPD) represents a significant cause of global
morbidity and mortality, with a substantial economic impact. Recent changes in the Global …
morbidity and mortality, with a substantial economic impact. Recent changes in the Global …
Tiotropium for stable chronic obstructive pulmonary disease: a meta-analysis
RG Barr, J Bourbeau, CA Camargo, FSF Ram - Thorax, 2006 - thorax.bmj.com
Background: A systematic review was undertaken to evaluate the efficacy of tiotropium, a
long acting anticholinergic drug, on clinical events, symptom scales, pulmonary function …
long acting anticholinergic drug, on clinical events, symptom scales, pulmonary function …
Novel long‐acting bronchodilators for COPD and asthma
M Cazzola, MG Matera - British journal of pharmacology, 2008 - Wiley Online Library
An important step in simplifying asthma and chronic obstructive pulmonary disease (COPD)
management and improving adherence with prescribed therapy is to reduce the dose …
management and improving adherence with prescribed therapy is to reduce the dose …
A pilot study to assess the effects of combining fluticasone propionate/salmeterol and tiotropium on the airflow obstruction of patients with severe-to-very severe COPD
M Cazzola, F Andò, P Santus, P Ruggeri… - Pulmonary …, 2007 - Elsevier
The aim of this pilot study was to explore the relative efficacy in terms of improvement in
symptoms and lung function of combining fluticasone propionate/salmeterol combination …
symptoms and lung function of combining fluticasone propionate/salmeterol combination …
QVA149 demonstrates superior bronchodilation compared with indacaterol or placebo in patients with chronic obstructive pulmonary disease
JA van Noord, R Buhl, C LaForce, C Martin, F Jones… - Thorax, 2010 - thorax.bmj.com
Background This randomised, double-blind, placebo controlled, four-period crossover study
assessed the efficacy and safety of once-daily QVA149, a dual bronchodilator consisting of …
assessed the efficacy and safety of once-daily QVA149, a dual bronchodilator consisting of …
The impact of severe exacerbations on quality of life and the clinical course of chronic obstructive pulmonary disease
DE Niewoehner - The American journal of medicine, 2006 - Elsevier
Severe exacerbations of chronic obstructive pulmonary disease (COPD) are morbid events
with slow recovery periods. They consume substantial healthcare resources, and they may …
with slow recovery periods. They consume substantial healthcare resources, and they may …
Ultra long-acting β2-agonists in development for asthma and chronic obstructive pulmonary disease
After the discovery of formoterol and salmeterol, new candidates for long-acting β2-
adrenoceptor agonists (LABAs) have emerged from various companies. In particular, once …
adrenoceptor agonists (LABAs) have emerged from various companies. In particular, once …
A review of the GOLD guidelines for the diagnosis and treatment of patients with COPD
L Fromer, CB Cooper - International journal of clinical practice, 2008 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is a leading cause of death in the USA, and
represents a major health, social and economic burden. COPD is underdiagnosed and often …
represents a major health, social and economic burden. COPD is underdiagnosed and often …