Gut microbiota in COVID-19: key microbial changes, potential mechanisms and clinical applications

F Zhang, RI Lau, Q Liu, Q Su, FKL Chan… - Nature Reviews …, 2023 - nature.com
The gastrointestinal tract is involved in coronavirus disease 2019 (COVID-19) caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The gut microbiota has …

Carotenoids and their health benefits as derived via their interactions with gut microbiota

A Eroglu, IS Al'Abri, RE Kopec, N Crook, T Bohn - Advances in Nutrition, 2023 - Elsevier
Carotenoids have been related to a number of health benefits. Their dietary intake and
circulating levels have been associated with a reduced incidence of obesity, diabetes …

Triggerable prodrug nanocoating enables on-demand activation of microbial and small-molecular therapeutics for combination treatment

X Kuang, Y Liu, H Luo, Q Li, F Wu… - Journal of the American …, 2023 - ACS Publications
The synergy of living microbial and small-molecular therapeutics has been widely explored
for treating a variety of diseases, while current combination strategies often suffer from low …

Genetically engineered bacterium: Principles, practices, and prospects

Y Liu, J Feng, H Pan, X Zhang, Y Zhang - Frontiers in Microbiology, 2022 - frontiersin.org
Advances in synthetic biology and the clinical application of bacteriotherapy enable the use
of genetically engineered bacteria (GEB) to combat various diseases. GEB act as a small …

Genetically engineered bacteria: a new frontier in targeted drug delivery

S Fooladi, N Rabiee, S Iravani - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Genetically engineered bacteria (GEB) have shown significant promises to revolutionize
modern medicine. These engineered bacteria with unique properties such as enhanced …

Intestinal delivery of probiotics: Materials, strategies, and applications

C Li, ZX Wang, H Xiao, FG Wu - Advanced Materials, 2024 - Wiley Online Library
Probiotics with diverse and crucial properties and functions have attracted broad interest
from many researchers, who adopt intestinal delivery of probiotics to modulate the gut …

Membrane vesicles derived from gut microbiota and probiotics: Cutting-edge therapeutic approaches for multidrug-resistant superbugs linked to neurological …

P Srivastava, K Kim - Pharmaceutics, 2022 - mdpi.com
Multidrug-resistant (MDR) superbugs can breach the blood–brain barrier (BBB), leading to a
continuous barrage of pro-inflammatory modulators and induction of severe infection-related …

Armored probiotics for oral delivery

X Yang, C Wang, Q Wang, Z Zhang, W Nie… - Smart …, 2023 - Wiley Online Library
As a kind of intestinal flora regulator, probiotics show great potential in the treatment of many
diseases. However, orally delivered probiotics are often vulnerable to unfriendly …

Microfluidic-based multifunctional microspheres for enhanced oral co-delivery of probiotics and postbiotics

X Yang, W Nie, C Wang, Z Fang, L Shang - Biomaterials, 2024 - Elsevier
Probiotic-based therapies have shown great potential in the prevention and treatment of
many diseases by positively regulating intestinal flora homeostasis. However, the efficacy of …

Recent advances in single-cell engineered live biotherapeutic products research for skin repair and disease treatment

MAM Roslan, MN Omar, NAM Sharif… - npj Biofilms and …, 2023 - nature.com
The human microbiome has emerged as a key player in maintaining skin health, and
dysbiosis has been linked to various skin disorders. Amidst growing concerns regarding the …