DNA origami
Biological materials are self-assembled with near-atomic precision in living cells, whereas
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …
Functionalizing DNA origami to investigate and interact with biological systems
DNA origami has emerged as a powerful method to generate DNA nanostructures with
dynamic properties and nanoscale control. These nanostructures enable complex …
dynamic properties and nanoscale control. These nanostructures enable complex …
[HTML][HTML] Polystyrene microplastics lead to pyroptosis and apoptosis of ovarian granulosa cells via NLRP3/Caspase-1 signaling pathway in rats
J Hou, Z Lei, L Cui, Y Hou, L Yang, R An… - Ecotoxicology and …, 2021 - Elsevier
Microplastics (MPs) considered as a new persistent environmental pollutant could enter into
the circulatory system and result in decrease of sperm quantity and quality in mice. However …
the circulatory system and result in decrease of sperm quantity and quality in mice. However …
Nanogels: Synthesis, properties, and recent biomedical applications
Nanogels, also termed hydrogel nanoparticles, have the properties and functions of both
nanomaterials and hydrogels. Till date, a considerable number of nanogels have been …
nanomaterials and hydrogels. Till date, a considerable number of nanogels have been …
A tubular DNA nanodevice as a siRNA/chemo‐drug co‐delivery vehicle for combined cancer therapy
Using the DNA origami technique, we constructed a DNA nanodevice functionalized with
small interfering RNA (siRNA) within its inner cavity and the chemotherapeutic drug …
small interfering RNA (siRNA) within its inner cavity and the chemotherapeutic drug …
[HTML][HTML] Nucleic acid nanoassembly-enhanced RNA therapeutics and diagnosis
M Zhao, R Wang, K Yang, Y Jiang, Y Peng, Y Li… - … Pharmaceutica Sinica B, 2023 - Elsevier
RNAs are involved in the crucial processes of disease progression and have emerged as
powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of …
powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of …
[HTML][HTML] Self-crosslinkable chitosan-hyaluronic acid dialdehyde nanoparticles for CD44-targeted siRNA delivery to treat bladder cancer
Y Liang, Y Wang, L Wang, Z Liang, D Li, X Xu, Y Chen… - Bioactive materials, 2021 - Elsevier
Bladder cancer is one of the concerning malignancies worldwide, which is lacking effective
targeted therapy. Gene therapy is a potential approach for bladder cancer treatment. While …
targeted therapy. Gene therapy is a potential approach for bladder cancer treatment. While …
Synthesis of siRNA nanoparticles to silence plaque-destabilizing gene in atherosclerotic lesional macrophages
Macrophages in atherosclerotic lesions promote plaque progression and are an attractive
therapeutic target in cardiovascular research. Here we present a protocol for synthesis of …
therapeutic target in cardiovascular research. Here we present a protocol for synthesis of …
DNA nanostructures: current challenges and opportunities for cellular delivery
A Lacroix, HF Sleiman - ACS nano, 2021 - ACS Publications
DNA nanotechnology has produced a wide range of self-assembled structures, offering
unmatched possibilities in terms of structural design. Because of their programmable …
unmatched possibilities in terms of structural design. Because of their programmable …