Nrf2 in cancers: A double‐edged sword

S Wu, H Lu, Y Bai - Cancer medicine, 2019 - Wiley Online Library
Abstract The Nrf2/Keap1 pathway is an important signaling cascade responsible for the
resistance of oxidative damage induced by exogenous chemicals. It maintains the redox …

Multifaceted role of one-carbon metabolism on immunometabolic control and growth during pregnancy, lactation and the neonatal period in dairy cattle

DN Coleman, AS Alharthi, Y Liang, MG Lopes… - Journal of animal …, 2021 - Springer
Dairy cattle undergo dramatic metabolic, endocrine, physiologic and immune changes
during the peripartal period largely due to combined increases in energy requirements for …

[HTML][HTML] Genome-wide association study on milk production and somatic cell score for Thai dairy cattle using weighted single-step approach with random regression …

S Buaban, K Lengnudum, W Boonkum… - Journal of Dairy …, 2022 - Elsevier
ABSTRACTS Genome-wide association studies are a powerful tool to identify genomic
regions and variants associated with phenotypes. However, only limited mutual confirmation …

Amino acids and the regulation of oxidative stress and immune function in dairy cattle

DN Coleman, V Lopreiato, A Alharthi… - Journal of Animal …, 2020 - academic.oup.com
The periparturient period is one of the most challenging periods in dairy cows and
encompasses the 3 wk prior to and 3 wk after parturition. The nutrient requirements of dairy …

Overview of the effect of rumen-protected limiting amino acids (methionine and lysine) and choline on the immunity, antioxidative, and inflammatory status of …

MZ Khan, S Liu, Y Ma, M Ma, Q Ullah, IM Khan… - Frontiers in …, 2023 - frontiersin.org
Overproduction of reactive oxygen species (ROS) is a well-known phenomenon
experienced by ruminants, especially during the transition from late gestation to successful …

Enhancing bovine immune, antioxidant and anti-inflammatory responses with vitamins, rumen-protected amino acids, and trace minerals to prevent periparturient …

MZ Khan, B Huang, X Kou, Y Chen, H Liang… - Frontiers in …, 2024 - frontiersin.org
Mastitis, the inflammatory condition of mammary glands, has been closely associated with
immune suppression and imbalances between antioxidants and free radicals in cattle …

Increased supply of methionine during a heat-stress challenge in lactating holstein cows alters mammary tissue mTOR signaling and its response to …

DN Coleman, M Vailati-Riboni, RT Pate… - Journal of animal …, 2022 - academic.oup.com
The first objective was to investigate the effects of feeding rumen-protected methionine
(RPM) during a heat stress (HS) challenge on abundance and phosphorylation of …

[HTML][HTML] Methionine alleviates heat stress-induced ferroptosis in bovine mammary epithelial cells through the Nrf2 pathway

J Xu, XL Wang, HF Zeng, ZY Han - Ecotoxicology and Environmental Safety, 2023 - Elsevier
Heat stress (HS) triggers mammary gland degradation, accompanied by apoptosis and
autophagy in bovine mammary epithelial cells, negatively affecting milk performance and …

Nano-selenium supplementation increases selenoprotein (Sel) gene expression profiles and milk selenium concentration in lactating dairy cows

L Han, K Pang, T Fu, CJC Phillips, T Gao - Biological Trace Element …, 2021 - Springer
Supplementation with selenium is common for dairy cows, but the importance of selenium
source is not clear. This study aimed to compare nano-selenium (Nano-Se) and sodium …

Taurine promotes milk synthesis via the GPR87-PI3K-SETD1A signaling in BMECs

M Yu, Y Wang, Z Wang, Y Liu, Y Yu… - Journal of Agricultural …, 2019 - ACS Publications
Taurine, a β-aminosulfonic acid, exerts many cellular physiological functions. It is still
unknown whether taurine can regulate milk synthesis in the mammary gland. Therefore, in …