Great strides have been made in recent years towards understanding the roles of natural
killer (NK) cells in immunity to tumours and viruses. NK cells are cytotoxic innate lymphoid …

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Natural killer (NK) cells are potent immune effector cells that can respond to infection and
cancer, as well as allowing maternal adaptation to pregnancy. In response to malignant …

Our understanding of development and function of natural killer (NK) cells has progressed
significantly in recent years. However, exactly how uterine NK (uNK) cells develop and …

Self versus non-self discrimination is a central theme in biology from plants to vertebrates,
and is particularly relevant for lymphocytes that express receptors capable of recognizing …

It is commonly believed that only T lymphocytes and B lymphocytes expressing
recombination-dependent antigen-specific receptors mediate contact hypersensitivity …

Natural killer (NK) cells play a key role in the immune response to certain infections and
malignancies by direct cytolysis of infected or transformed cells and by secretion of potent …

KIR genes have evolved in primates to generate a diverse family of receptors with unique
structures that enable them to recognize MHC-class I molecules with locus and allele …

Natural killer (NK) cells, similar to other lymphocytes, acquire tolerance to self. This means
that NK cells have the potential to attack normal self cells but that there are mechanisms to …

Natural killer (NK) cells attack tumor and infected cells, but the receptors and ligands that
stimulate them are poorly understood. Here we report the expression cloning of two murine …