Left ventricular remodelling post-myocardial infarction: pathophysiology, imaging, and novel therapies
S Frantz, MJ Hundertmark… - European heart …, 2022 - academic.oup.com
Most patients survive acute myocardial infarction (MI). Yet this encouraging development
has certain drawbacks: heart failure (HF) prevalence is increasing and patients affected tend …
has certain drawbacks: heart failure (HF) prevalence is increasing and patients affected tend …
[HTML][HTML] CXCR4-directed theranostics in oncology and inflammation
Given its prominent role in inflammation and cancer biology, the CXC motif chemokine
receptor 4 (CXCR4) has gained a lot of attention in the recent years. This review gives a …
receptor 4 (CXCR4) has gained a lot of attention in the recent years. This review gives a …
[HTML][HTML] Myocardial infarction triggers cardioprotective antigen-specific T helper cell responses
M Rieckmann, M Delgobo, C Gaal… - The Journal of …, 2019 - Am Soc Clin Investig
T cell autoreactivity is a hallmark of autoimmune diseases but can also benefit self-
maintenance and foster tissue repair. Here, we investigated whether heart-specific T cells …
maintenance and foster tissue repair. Here, we investigated whether heart-specific T cells …
Molecular imaging visualizes recruitment of inflammatory monocytes and macrophages to the injured heart
Rationale: Paradigm shifting studies have revealed that the heart contains functionally
diverse populations of macrophages derived from distinct embryonic and adult …
diverse populations of macrophages derived from distinct embryonic and adult …
[HTML][HTML] PET imaging in cardiac sarcoidosis: a narrative review with focus on novel PET tracers
P Saric, KA Young, M Rodriguez-Porcel… - Pharmaceuticals, 2021 - mdpi.com
Sarcoidosis is a multi-system inflammatory disease characterized by the development of
inflammation and noncaseating granulomas that can involve nearly every organ system …
inflammation and noncaseating granulomas that can involve nearly every organ system …
[HTML][HTML] CXCR4-targeted theranostics in oncology
A growing body of literature reports on the upregulation of CXC motif chemokine receptor 4
(CXCR4) in a variety of cancer entities, rendering this receptor as suitable target for …
(CXCR4) in a variety of cancer entities, rendering this receptor as suitable target for …
[HTML][HTML] CXCR4-directed imaging in solid tumors
Despite histological evidence in various solid tumor entities, available experience with
CXCR4-directed diagnostics and endoradiotherapy mainly focuses on hematologic …
CXCR4-directed diagnostics and endoradiotherapy mainly focuses on hematologic …
[HTML][HTML] In vivo targeting of CXCR4—new horizons
M Schottelius, K Herrmann, C Lapa - Cancers, 2021 - mdpi.com
Simple Summary Beyond its pre-eminent role in the context of tumor cell growth as well as
metastasis, the CXC motif chemokine receptor 4 (CXCR4) is a key player in the …
metastasis, the CXC motif chemokine receptor 4 (CXCR4) is a key player in the …
[HTML][HTML] Imaging inflammation with positron emission tomography
J Iking, M Staniszewska, L Kessler, JM Klose… - Biomedicines, 2021 - mdpi.com
The impact of inflammation on the outcome of many medical conditions such as
cardiovascular diseases, neurological disorders, infections, cancer, and autoimmune …
cardiovascular diseases, neurological disorders, infections, cancer, and autoimmune …
[HTML][HTML] Regional analysis of inflammation and contractile function in reperfused acute myocardial infarction by in vivo 19F cardiovascular magnetic resonance in pigs
F Bönner, M Gastl, F Nienhaus, M Rothe… - Basic Research in …, 2022 - Springer
Inflammatory cell infiltration is central to healing after acute myocardial infarction (AMI). The
relation of regional inflammation to edema, infarct size (IS), microvascular obstruction …
relation of regional inflammation to edema, infarct size (IS), microvascular obstruction …