Proteomics by mass spectrometry: approaches, advances, and applications

JR Yates, CI Ruse… - Annual review of …, 2009 - annualreviews.org
Mass spectrometry (MS) is the most comprehensive and versatile tool in large-scale
proteomics. In this review, we dissect the overall framework of the MS experiment into its key …

Comprehensive multidimensional liquid chromatography: theory and applications

P Dugo, F Cacciola, T Kumm, G Dugo… - … of Chromatography A, 2008 - Elsevier
Comprehensive two-dimensional (2D) liquid chromatographic (LC× LC) techniques can be
considered innovative methods only recently developed and adopted in many …

Effect of sampling rate on resolution in comprehensive two-dimensional liquid chromatography

RE Murphy, MR Schure, JP Foley - Analytical Chemistry, 1998 - ACS Publications
In “comprehensive” two-dimensional liquid chromatography, the column effluent from the
first separation system (the first dimension) is sequentially sampled by the second …

Fabricating large arrays of microwells with arbitrary dimensions and filling them using discontinuous dewetting

RJ Jackman, DC Duffy, E Ostuni, ND Willmore… - Analytical …, 1998 - ACS Publications
This paper describes the fabrication of large (up to 45 cm2) arrays of microwells, with
volumes as small as∼ 3 fL/well and densities as high as 107 wells/cm2. These arrays of …

Chemical cross‐linking and mass spectrometry for mapping three‐dimensional structures of proteins and protein complexes

A Sinz - Journal of mass spectrometry, 2003 - Wiley Online Library
Chemical cross‐linking of proteins, an established method in protein chemistry, has gained
renewed interest in combination with mass spectrometric analysis of the reaction products …

[图书][B] Chromatography: Fundamentals and applications of chromatography and related differential migration methods-Part B: Applications

E Heftmann - 2004 - books.google.com
Chromatography has emerged as the most important and versatile analytical method. The
book is not only an updated version of Heftmann's classical text, but it covers areas of future …

Multidimensional separations-based shotgun proteomics

ML Fournier, JM Gilmore, SA Martin-Brown… - Chemical …, 2007 - ACS Publications
The proteome refers to the collection of proteins in a given biological organism or system
under a particular set of environmental conditions. The study of proteins, referred to as …

Comprehensive on-line LC/LC/MS of proteins

GJ Opiteck, KC Lewis, JW Jorgenson… - Analytical …, 1997 - ACS Publications
This is a description of a comprehensive two-dimensional liquid chromatography (LC)
system for the separation of protein mixtures. This system uses cation-exchange …

Comprehensive two-dimensional liquid chromatography in analysis of Lamiaceae herbs: Characterisation and quantification of antioxidant phenolic acids

M Kivilompolo, T Hyötyläinen - Journal of Chromatography A, 2007 - Elsevier
A fast and effective dynamic sonication assisted ethanol extraction method was developed
for extracting phenolic acids from basil, oregano, rosemary, sage, spearmint and thyme of …

Microcolumn liquid chromatography: instrumentation, detection and applications

JPC Vissers, HA Claessens, CA Cramers - Journal of Chromatography a, 1997 - Elsevier
This review discusses many different aspects of microcolumn liquid chromatography (LC)
and reflects the areas of microcolumn LC research interest over the past decades. A brief …