Atherosclerotic lower extremity peripheral artery disease (PAD) is increasingly recognized
as an important cause of cardiovascular morbidity and mortality that affects> 230 million …

Platelets are key mediators of atherothrombosis, yet, limited tools exist to identify individuals
with a hyperreactive platelet phenotype. In this study, we investigate the association of …

Background: Few effective therapies exist to improve lower extremity muscle pathology and
mobility loss due to peripheral artery disease (PAD), in part because mechanisms …

Peripheral arterial disease (PAD), a manifestation of systemic atherosclerosis, is
underdiagnosed in the general population. Despite the extensive research performed to …

BACKGROUND: Lower extremity peripheral artery disease (PAD) is a growing epidemic
with limited effective treatment options. Here, we provide a single-nuclei atlas of PAD limb …

BACKGROUND: Kawasaki disease (KD) and multisystem inflammatory syndrome in
children (MIS-C) share similar clinical manifestations, including cardiovascular …

Peripheral artery disease (PAD) affects 10 mil-lion people in the United States and> 230
million worldwide. 1, 2 It is associated with impaired vascular perfusion to the lower …

Peripheral arterial diseases (PADs) are complex cardiovascular conditions influenced by
environmental factors and somatic mutations in multiple genes involved in hematopoiesis …

Peripheral artery disease (PAD), a significant health burden worldwide, affects lower
extremities due to atherosclerosis in peripheral vessels. Although the mechanisms of PAD …

Background Psoriasis is an inflammatory skin disease associated with increased
cardiovascular (CV) risk, whose pathogenesis is not fully known. Objective We identified a …