Hemoglobin E (HbE) is an extremely common structural hemoglobin variant that occurs at
high frequencies throughout many Asian countries. It is a β-hemoglobin variant, which is …

Beta-thalassaemia causes defective haemoglobin synthesis leading to ineffective
erythropoiesis, chronic haemolytic anaemia, and subsequent clinical complications. Blood …

Given the rapidly rising healthcare costs, it is important to understand the economic costs of
hematopoietic cell transplantation (HCT), a procedure that is being used more frequently in …

Thalassemia-free survival after allogeneic stem cell transplantation (SCT) is about 80–90%
with either matched-related or-unrelated donors. We explored the use of a mismatched …

Fifty-five years after publication of the first hematopoietic stem cell transplantation this
technique has become an accepted treatment option for defined hematologic and non …

Sustained donor engraftment after allogeneic hematopoietic cell transplantation (HCT)
converts to healthy donor hemoglobin synthesis and halts disease symptoms in patients with …

Both a-thalassemia and b-thalassemia and some abnormal hemoglobins (Hb), such as Hb E
and Hb Constant Spring (CS), are prevalent in Thailand. The frequencies are 20% to 30 …

BACKGROUND The objective was to estimate the incidence‐based costs of treating β‐
thalassemia major (BTM) to the United Kingdom's National Health Service (NHS) over the …

Severe blood disorders and cancer are the leading cause of death and disability from
noncommunicable diseases in the global pediatric population and a major financial burden …

Background A previous cost-effectiveness analysis (CEA) showed that Pneumococcal
Conjugate Vaccine (PCV) 10 and PCV13 were not cost-effective for universal immunization …