Flavonoids are natural plant-derived dietary bioactive compounds having a substantial
impact on human health. Morin hydrate is a bioflavonoid mainly obtained from fruits, stem …

Morin is a natural polyphenol, originally isolated from members of the Moraceae family that
can be extracted from leaves, fruits, stems and branches of numerous plants. Several …

Ifosfamide (IFA), a commonly used chemotherapeutic drug, has been frequently associated
with encephalopathy and central nervous system toxicity. The present study aims to …

Diabetic retinopathy (DR) is one of the leading causes of decreased vision and blindness
worldwide. Diabetes-induced oxidative stress is believed to be the key factor that initiates …

Neurodegenerative diseases are one of the leading causes of disability and death
worldwide. Intracellular transduction pathways that end in the activation of specific …

Silver nanoparticles (AgNPs) have been widely produced for different industrial purposes.
Recently, biogenic synthesis of AgNPs has emerged although the extent of effects from …

Diabetes and its complications are caused by chronic glucotoxicity driven by persistent
hyperglycemia. In this article, we review the mechanisms of diabetic glucotoxicity by …

Inflammation is a natural, carefully orchestrated response of the organism to tissue damage,
involving various signaling systems and the recruitment of inflammatory cells. These cells …

Intervertebral disc degeneration (IDD) is a major cause of lower back pain (LBP), a condition
that causes a heavy economic burden globally. The production of cytokines, including …

Tumor necrosis factor-alpha (TNF-α) is a well-known pro-inflammatory cytokine responsible
for the modulation of the immune system. TNF-α plays a critical role in almost every type of …