A study of survival strategies for improving acclimatization of lowlanders at high-altitude

P Sharma, S Mohanty, Y Ahmad - Heliyon, 2023 - cell.com
Human Acclimatization and therapeutic approaches are the core components for
conquering the physiological variations at high altitude (≥ 2500 m) exposure. The declined …

Salidroside attenuates high altitude hypobaric hypoxia-induced brain injury in mice via inhibiting NF-κB/NLRP3 pathway

S Jiang, F Fan, L Yang, K Chen, Z Sun, Y Zhang… - European Journal of …, 2022 - Elsevier
Salidroside (Sal), an active ingredient from Rhodiola crenulate, has been reported to exert
neuroprotection in cerebral injury from hypobaric hypoxia (HH) at high altitude. However, it …

Progress in the treatment of high altitude cerebral edema: Targeting REDOX homeostasis

Y Li, C Li, T Luo, T Yue, W Xiao, L Yang… - Journal of …, 2023 - Taylor & Francis
With the increasing of altitude activities from low-altitude people, the study of high altitude
cerebral edema (HACE) has been revived. HACE is a severe acute mountain sickness …

Protective effect of 5, 6, 7, 8-Tetrahydroxyflavone on high altitude cerebral edema in rats

L Jing, N Wu, J Zhang, Q Da, H Ma - European Journal of Pharmacology, 2022 - Elsevier
High altitude cerebral edema (HACE) is a potentially life-threatening disease encountered at
high altitudes. However, effective methods for HACE prophylaxis are limited. Convincing …

Study of high-altitude cerebral edema using multimodal imaging

C Long, H Bao - Frontiers in Neurology, 2023 - frontiersin.org
Objective To analyze the brain imaging features of high-altitude cerebral edema (HACE)
using computed tomography (CT) and multi-sequence magnetic resonance imaging (MRI) …

[HTML][HTML] Challenges in the management of high-altitude illnesses and emergencies in Bhutan and Nepal

T Dorji, S Giri, U Tshering, S LeVine, S Chhetri… - Travel Medicine and …, 2023 - Elsevier
Many popular tourist attractions and trekking routes in Bhutan and Nepal are situated
between 3000 and 6000 m in elevation. High-altitude emergencies are becoming more …

Effect of butylphthalide on prevention and treatment of high altitude cerebral edema in rats

B Ma, Q Li, M Li, J Wang, N Fan, S Yang, W Shi… - Heliyon, 2024 - cell.com
n-butylphthalide (NBP) contains one of the main active ingredients of celery seed. It has a
series of pharmacological mechanisms, including reconstitution of microcirculation …

[HTML][HTML] Transcriptome of pituitary function changes in rat model of high altitude cerebral edema

Y Peng, H Yin, S Li, H Yang - Genomics, 2022 - Elsevier
High altitude cerebral edema (HACE) is a serious subtype of acute mountain sickness
(AMS). Studies have suggested that increased expression of corticotropin releasing …

Does altitude have an effect on stroke mortality and hospitalization risk? A comprehensive evaluation of United States data

J Gerken, N Huber, D Zapata, IG Barron, I Zapata - Frontiers in Stroke, 2023 - frontiersin.org
Background Globally, stroke is a leading cause of death among people over 50 years of
age. In the United States alone, over 150,000 people die due to stroke every year …

Vertebrobasilar artery elongation in migraine—a retrospective cross-sectional study

O Hensel, P Burow, T Kraya, D Stoevesandt… - Acta Neurologica …, 2023 - Springer
Background Numerous but inconclusive findings have sparked an ongoing debate about
whether the arteries of migraine patients undergo vascular alterations. The outlet angle of …