Heme oxygenase-1 signaling and redox homeostasis in physiopathological conditions
V Consoli, V Sorrenti, S Grosso, L Vanella - Biomolecules, 2021 - mdpi.com
Heme-oxygenase is the enzyme responsible for degradation of endogenous iron
protoporphyirin heme; it catalyzes the reaction's rate-limiting step, resulting in the release of …
protoporphyirin heme; it catalyzes the reaction's rate-limiting step, resulting in the release of …
Preeclampsia: updates in pathogenesis, definitions, and guidelines
E Phipps, D Prasanna, W Brima… - Clinical Journal of the …, 2016 - journals.lww.com
Preeclampsia is becoming an increasingly common diagnosis in the developed world and
remains a high cause of maternal and fetal morbidity and mortality in the developing world …
remains a high cause of maternal and fetal morbidity and mortality in the developing world …
A review on heme oxygenase-1 induction: is it a necessary evil
Abstract Heme oxygenase-1 (HO-1) is considered to be the main protein in diseases arising
as a result of oxidative and inflammatory insults. Tremendous research has been carried out …
as a result of oxidative and inflammatory insults. Tremendous research has been carried out …
[HTML][HTML] Targeting the transcription factor Nrf2 to ameliorate oxidative stress and inflammation in chronic kidney disease
S Ruiz, PE Pergola, RA Zager, ND Vaziri - Kidney international, 2013 - Elsevier
Oxidative stress and inflammation are mediators in the development and progression of
chronic kidney disease (CKD) and its complications, and they are inseparably linked as …
chronic kidney disease (CKD) and its complications, and they are inseparably linked as …
Vascular mechanisms and molecular targets in hypertensive pregnancy and preeclampsia
H Qu, RA Khalil - American Journal of Physiology-Heart and …, 2020 - journals.physiology.org
Preeclampsia is a major complication of pregnancy manifested as hypertension and often
intrauterine growth restriction, but the underlying pathophysiological mechanisms are …
intrauterine growth restriction, but the underlying pathophysiological mechanisms are …
Mitochondrial dysfunction in diabetes: from molecular mechanisms to functional significance and therapeutic opportunities
WI Sivitz, MA Yorek - Antioxidants & redox signaling, 2010 - liebertpub.com
Given their essential function in aerobic metabolism, mitochondria are intuitively of interest
in regard to the pathophysiology of diabetes. Qualitative, quantitative, and functional …
in regard to the pathophysiology of diabetes. Qualitative, quantitative, and functional …
[PDF][PDF] Adult stem cells: hopes and hypes of regenerative medicine
Stem cells are self-renewing cells that can differentiate into specialized cell type (s).
Pluripotent stem cells, ie embryonic stem cells (ESC) or induced pluripotent stem cells …
Pluripotent stem cells, ie embryonic stem cells (ESC) or induced pluripotent stem cells …
Heme oxygenases in cardiovascular health and disease
Heme oxygenases are composed of two isozymes, Hmox1 and Hmox2, that catalyze the
degradation of heme to carbon monoxide (CO), ferrous iron, and biliverdin, the latter of …
degradation of heme to carbon monoxide (CO), ferrous iron, and biliverdin, the latter of …
Heme oxygenase-1 regulates cardiac mitochondrial biogenesis via Nrf2-mediated transcriptional control of nuclear respiratory factor-1
CA Piantadosi, MS Carraway, A Babiker… - Circulation …, 2008 - Am Heart Assoc
Heme oxygenase (HO)-1 is a protective antioxidant enzyme that prevents cardiomyocyte
apoptosis, for instance, during progressive cardiomyopathy. Here we identify a fundamental …
apoptosis, for instance, during progressive cardiomyopathy. Here we identify a fundamental …
The endothelium, Part I: Multiple functions of the endothelial cells--focus on endothelium-derived vasoactive mediators
M Félétou - 2011 - books.google.com
The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the
blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in …
blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in …